In one case a horse ate ergoted hay: next day the left hind leg was stiff, and moist with cold sweat; on the second day it was badly swollen and gangrene of all the tissues became apparent, and after the skin of the leg and a considerable part of the muscular tissue had sloughed off the animal died on the third day. In other cases horses showed symptoms twenty-four hours after eating ergoted hay: fatigue, indisposition to work, cold sweat, particularly on the neck, paralysis of the tongue and muscles concerned in swallowing, and then generalized paralysis, very slow and deep respiration, subnormal temperature, normal pulse at first and then weaker till scarcely distinguishable, death in six or eight hours (Chesnut and Wilcox). According to Pammel ergotism manifests itself among animals chiefly in the chronic form, the poison being acquired in small amounts and accumulation taking place slowly. Two distinct forms of the disease are recognized, the spasmodic and gangrenous. “Symptoms referable to the digestive tract, such as nausea, vomiting, colic, diarrhœa, or constipation occur in both forms. Pregnant animals very frequently abort.” “In the spasmodic type of the disease, symptoms due to overstimulation of the central nervous system appear. These are tonic contraction of the flexor tendons of the limbs, anæsthesia of the extremities, muscular trembling, general tetanic spasms, convulsions and delirium. Death usually occurs from secondary causes.” “Gangrenous ergotism is characterised by coldness and anæsthesia of the extremities, followed ultimately by dry gangrene of these parts. The effects of this dry gangrene are often very serious and amount to sloughing of the feet, tips of the ears, tip of the tail, shedding of the hair, teeth, etc. Death takes place from exhaustion. “Acute poisoning is characterized by vomiting (in dogs), profuse salivation, dilatation of the pupils, rapid breathing and frequent pulse. The animal cries out, has convulsive twitchings, staggering gait, paraplegia, intense thirst and coma, terminating in death.”