In 1810 Dr. Thacher published “The American Dispensatory,” and in 1812 “Observations on Hydrophobia.” In 1817 he published “The Modern Practice of Physic,” in 1822 the “American Orchardist,” and in 1823 “A Military Journal during the Revolutionary War,” in 1828 “American Medical Biography,” in 1829, “A Practical Treatise on the Management of Bees,” in 1831, “An Essay on Demonology, Ghosts, Apparitions and Popular Superstitions,” and in 1832 a “History of the Town of Plymouth.” Of some of these books second editions have been published; some are standard works, and all are rare. The suggestion I have made that he was in advance of his time is confirmed by his work on hydrophobia, in which more than a hint is given that methods of prevention or cure might be successfully adopted, such as Pasteur has in recent years advocated. In that work the following passage may be found: “Experiments made upon the canine poison in brutes might be considered as an arduous and hazardous undertaking, but it is not to be deemed altogether impracticable, and I will suggest the following project for the purpose. In the first place dogs when affected with madness, instead of being killed, should be confined and secured that the disease may run its course, and for the ascertainment of many useful facts connected with its several stages. If experiments on dogs should be deemed too hazardous let other animals of little value be selected, provided a sufficient number can be procured. Having provided for their security in some proper enclosure, let them be inoculated with the saliva of the mad dog. With some the inoculated part might be cut out at different stages to ascertain the latest period at which it may be done successfully. To others, various counter poisons and specific remedies might be applied to the wound and administered internally. In fact it would be difficult to determine _a priori_, the extent of the advantages of this novel plan if judiciously conducted. You may smile at my project, but however chimerical and visionary it may appear, I would rejoice to be the Jenner of the proposed institution; though I might fail in realizing my thousands I could pride myself in being the candidate for the honor, and the author of an attempt to mitigate the horrors attending one of the greatest of all human calamities.”