Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and ExpertsBlyth, Alexander Wynter
Science
Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and Experts
Blyth, Alexander Wynter
Poisons
§ 163. =Excretion of Alcohol.=--Alcohol, in the diluted form, is quickly
absorbed by the blood-vessels of the stomach, &c., and circulates in the
blood; but what becomes of it afterwards is by no means settled. I think
there can be little doubt that the lungs are the main channels through
which it is eliminated; with persons given up to habits of intemperance,
the breath has constantly a very peculiar ethereal odour, probably
dependent upon some highly volatile oxidised product of alcohol.
Alcohol is eliminated in small proportion only by the kidneys.
Thudichum, in an experiment[152] by which 4000 grms. of absolute alcohol
were consumed by thirty-three men, could only find in the collected
urine 10 grms. of alcohol. The numerous experiments by Dupré also
establish the same truth, that but a fraction of the total alcohol
absorbed is excreted by the kidneys. According to Lallemand, Perrin, and
Duroy the content of the brain in alcohol is more than that of the
other organs. I have found also that the brain after death has a
wonderful attraction for alcohol, and yields it up at a water-heat very
slowly and with difficulty. In one experiment, in which a finely-divided
portion of brain, which had been soaking in alcohol for many weeks, was
submitted to a steam heat of 100°, twenty-four hours’ consecutive
heating failed to expel every trace of spirit.
[152] See Thudichum’s _Pathology of the Urine_, London, 1877, in which
both his own and Dr. Dupré’s experiments are summarised.
It is probable that true alcoholates of the chemical constituents of the
brain are formed. In the case of vegetable colloidal bodies, such, for
example, as the pulp of cherries, a similar attraction has been
observed, the fruit condensing, as it were, the alcohol in its own
tissues, and the outer liquid being of less alcoholic strength than that
which can be expressed from the steeped cherries. Alcohol is also
excreted by the sweat, and minute fractions have been found in the
fæces.
§ 164. =Toxicological Detection of Alcohol= (see “Foods,” pp.
406-419).--The living cells of the body produce minute quantities of
alcohol, as also some of the bacteria normally inhabiting the small
intestine produce small quantities of alcohol, and it is often found in
traces in putrefying fluids. Hence, mere qualitative proofs of the
presence of alcohol are insufficient on which to base an opinion as to
whether alcohol had been taken during life or not, and it will be
necessary to estimate the quantity accurately by some of the processes
detailed in “Foods,” p. 409, _et seq._ In those cases in which alcohol
is found in quantity in the stomach, there can, of course, be no
difficulty; in others, the whole of the alcohol may have been absorbed,
and chemical evidence, unless extremely definite, must be supplemented
by other facts.
2. AMYLIC ALCOHOL.
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