Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and ExpertsBlyth, Alexander Wynter
Science
Poisons, Their Effects and Detection: A Manual for the Use of Analytical Chemists and Experts
Blyth, Alexander Wynter
Poisons
§ 172. =Ether as an Anæsthetic.=--Ether is now much used as an
anæsthetic, and generally in conjunction with chloroform. Anæsthesia by
ether is said to compare favourably with that produced by chloroform. In
92,000 cases of operations performed under ether, the proportion dying
from the effects of the anæsthetic was only ·3 per 10,000 (Morgan),
while chloroform gives a higher number (see p. 149). The mortality in
America, again, from a mixture of chloroform and ether in 11,000 cases
is reckoned at 1·7 per 10,000; but this proportion is rather above some
of the calculations relative to the mortality from pure chloroform, so
that the question can hardly be considered settled. The symptoms of
ether narcosis are very similar to those produced by chloroform. The
chief point of difference appears to be its action on the heart. Ether,
when first breathed, stimulates the heart’s action, and the
after-depression that follows never reaches so high a grade as with
chloroform. Ether is said to kill by paralysing the respiration, and in
cases which end fatally the breathing is seen to stop suddenly:
convulsions have not been noticed. The _post-mortem_ appearances, as in
the case of chloroform, are not characteristic.
§ 173. =Separation of Ether from Organic Fluids, &c.=--Despite the low
boiling-point of ether, it is by no means easy to separate it from
organic substances _so as to recover the whole of the ether present_.
The best way is to place the matters in a flask connected with an
ordinary Liebig’s condenser, the tube of the latter at its farther end
fitting closely into the doubly perforated cork of a flask. Into the
second perforation is adapted an upright tube about 2 feet long, which
may be of small diameter, and must be surrounded by a freezing mixture
of ice and salt. The upper end of this tube is closed by a thistle-head
funnel with syphon, and in the bend of the syphon a little mercury
serves as a valve. Heat is now applied to the flask by means of a
water-bath, and continued for several hours; the liquid which has
distilled over is then treated with dry calcic chloride and redistilled
exactly in the same way. To this distillate again a similar process may
be used, substituting dry potassic carbonate for the calcic chloride. It
is only by operating on these principles that the expert can recover in
an approximate state of anhydrous purity such a volatile liquid. Having
thus obtained it pure, it may be identified (1) by its smell, (2) by its
boiling-point, (3) by its inflammability, and (4) by its reducing
chromic acid. The latter test may be applied to the vapour. An asbestos
fibre is soaked in a mixture of strong sulphuric acid and potassic
dichromate, and then placed in the tube connected with the flask--the
ethereal (or alcoholic) vapour passing over the fibre, immediately
reduces the chromic acid to chromic oxide, with the production of a
green colour.
V.--Chloroform.
CHLOROFORM, TRICHLOROMETHANE OR METHENYL CHLORIDE (CHCl₃).
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