THIS is the most prevalent of all derangements of the female economy, connected with the uterine system; and from its debilitating effects, induces a train of maladies that tend to embitter personal comfort more than any other human ill. Leucorrhœa consists of a discharge of acrid, or bland, but variously-colored mucus from the vagina, differing in intensity according to the cause and duration. It would be idle to offer the many arguments set up to prove whence it proceeds, or to examine the discussions as to whether it is the produce of the uterine vessels, or the vaginal secretives. That both aid in its formation is doubtless the case (as the employment of the speculum has satisfactorily proved); and equally certain that, according to the amount of irritability existing therein, so depends the quantity and character of the discharge. It exists in the married and single—in the moral and unchaste; and therefore the cause should be cautiously divined, it being evident that other than sexual indulgences establish this annoying and distressing affliction. It may be fairly conceded to be a vitiated secretion, depending upon a weakened state of the local vessels, and, moreover, in particular habits, to be a salutary evacuation. On the other hand, it must not be denied that it is oftentimes, where it occurs to persons living _sub judice mariti_, the result of sexual intemperance, or disease springing from an indiscriminate indulgence in the same. However, as my purpose is more with the symptoms and treatment, the following may be received as a summary of what occurs, and what should be done for the removal thereof:— In addition to the discharge, which at one time is scanty, at another profuse, there are usually severe pains in the loins and lower part of the abdomen: there is a sense of bearing down, as though the womb were descending and even protruding. The general health of the patient is disturbed, loss of appetite, excessive languor, a pale and emaciated look, sleepless nights, dark areola around the eyes, various hysterical and other nervous affections, and numerous disturbances indicating a weakened and impaired state of mind and body. Among other causes beside those alluded to, may be enumerated irregular living, late hours, mental and bodily fatigue, deficient exercise, impure air, and neglect of personal ablution. Among the consequences of a long-continued leucorrhœa, an almost certainty of sterility should not be omitted. _Treatment._—In leucorrhœa, where or where not consecutive to gonorrhœa, depending on loss of tone of the secretive vessels of the internal organs of generation, the chief indication is to impart vigor and restore strength, which it is evident depends much upon an avoidance of those causes that first started the disease.