The accompanying sketch portrays, perhaps, more the seat of the disease when attacking the upper part of the body, than the appearance; for to give a true portraiture, the drawing should be the size of life, and colored after nature. It is, however, I doubt not, sufficient to exemplify the site of the disorder. The eruption is smaller on the face, and less vicious, generally, than on the body; but it proves most unsightly, and indicates great advancement of the disease. The legs (see next page), and those parts of the skin least vascular, assume a mottled appearance resembling recent bruises; at other times, clusters of spots like grapes hanging together. The shoulders, arms, and wrists, also present a somewhat similar appearance; though perhaps not to the same extent, owing to being more warmly clad, and less in exercise, than the lower extremity. When the disease extends to the hands, it is marked by exfoliations of the palm, with occasional deep cracks that cause much pain. Nor are the fingers and nails exempt from this encroaching malady, which, during its occupation, shows itself by a redness under the nail, that at last ends in the destruction of the nail. [Illustration] [Illustration] [Illustration] The head, also, is a frequent seat of the disorder. It is generally discovered by running the hands through the hair, when a little crust will be detected by the fingers, or a slight itching will show its position, or the brush may break it off. The top and hind parts of the head are generally the situations selected. Occasionally the hair will fall off, leaving spots of a smooth baldness. [Illustration] The vital organs, fortunately, are never subject to syphilitic inflammation—such as the brain, the viscera of the chest, and abdomen; nor is even the mucous membrane of the interior of the body affected, its power being confined solely to those parts or structures subject to the influence of external causes. When the venereal virus attacks the throat or palate, the membrane of the roof of the mouth becomes red and inflamed, patches ulcerate, and, if not cured, sooner or later expose the bony palate, which may be felt by the probe. This is the first stage. The exposed bone next exfoliates, and a communication is thereby formed between the mouth and nose, the fluids return through it, the voice is changed into a nasal twang, and a most offensive discharge is secreted. [Illustration] This drawing represents ulceration of the tonsils, uvula, and arch of the palate; also the edges of the tongue. The drawing, p. 102, shows the under surface of the tongue, the inner part of the lower lip, and the lower gums affected with venereal ulcers.