In Portugal a splendid dawn ushered in the sixteenth century. The discovery of the sea route to India, while it gave an impulse to science and literature, also increased religious fervour, since the Portuguese who contended against the Moors in India were but carrying on the work of their ancestors five centuries earlier in Portugal. Old-fashioned Portugal thus only gradually welcomed the Renaissance and stood firm against the Reformation. But in the reign of João III (1521-57) the University of Coimbra came to be one of the best-known universities in Europe. André de Gouvêa (†1548), whom Montaigne called ‘sans comparaison le plus grand principal de France’,[219] and Diogo de Teive returned from the Collège de Sainte-Barbe to inaugurate its studies, and many of its chairs were offered to distinguished Portuguese and foreign scholars, such as Ayres Barbosa (†1540) and George Buchanan (1506-82), as well as to Portuguese humanists such as Antonio de Gouvêa and Achilles Estaço (†1581). Nicholas Cleynarts or Nicolaus Clenardus (1493 or 1494-1542), Professor of Greek and Hebrew at Louvain, came to Portugal from Salamanca as tutor to the Infante Henrique in 1533, and from Portugal wrote some of his wittiest letters.[220] He found Coimbra a second Athens, and few great Portuguese writers of the century had not spent some years there or at the University before it was transferred to Coimbra from Lisbon in 1537. King João III and especially his son, the young prince João (1537-54), Cardinal Henrique (1512-80), and the many-sided Infante Luis (1506-55), _favorecedor de toda habilidad_, himself a poet of no mean order[221] and pupil of Pedro Nunez, eagerly patronized letters; the household of the accomplished Infanta Maria (1521-77) became the ‘home of the Muses’[222]; learned Luisa Sigea (†1560), of French origin, but born at Toledo and brought up in Portugal, wrote a Latin poem in praise of _Syntra_; her sister Angela, Joana Vaz, and Publia Hortensia de Castro were likewise noted for their learning, and D. Lianor de Noronha (1488-1563), daughter of Fernando, Marques de Villareal, did good service to Portuguese prose by her encouragement of translations. But Portuguese literature lost something by its latinization, and it is pleasant to turn back half a century to a time when it was humbler and more national. The ‘very prosperous’ Manuel I, Lord of the Ocean,[223] Lord of the East,[224] had been seven years king, Vasco da Gama had returned triumphantly from Calicut (1497-9), Cabral had discovered Brazil for Portugal (1500), Afonso de Albuquerque (†1515) stood on the threshold of his career of conquests and glory, the Portuguese Empire was advancing from North Africa to China,[225] the gold and spices were beginning to arrive in plenty from the East, and hope of honour and riches was drawing nobleman and peasant to Lisbon, when GIL VICENTE (_c._ 1465-1536?) introduced the drama into his