After having shown that Madame could not have been poisoned, it remains to settle what disease it was of which she died. Our task is simplified by the marvellous study in which Littré proved that she succumbed to an acute peritonitis, the immediate and inevitable result of the perforation of the stomach by an ulcer. This study, Dr. Paul Le Gendre tells us, is the finest extant example of a retrospective medical demonstration. We have it now under our eyes; but we find it condensed by the pen of the most elegant writer of our time, M. Anatole France, who will allow us to borrow this quotation: 'Littré, an expert in medical observation, does not hesitate to diagnose a simple ulceration of the stomach, which Professor Cruveilhier was the first to describe, and which Madame's physicians could not recognise because they knew nothing about it. It is unquestionable that for some time Madame had been suffering from abdominal pains after her meals. The liquid she took on June 29 brought about the perforation of the ulcerated wall, and this caused the terrible pain in her side and the peritonitis which we have mentioned. The physicians who opened the body found, indeed, that the stomach was pierced with a little hole; but as they could not account for the pathological origin of this hole, they fancied after the event that it had been made inadvertently during the autopsy, "upon which," says the surgeon of the king of England, "I was the only one to insist." The incident is reported as follows by the Abbé Bourdelot: "It happened by misadventure during the dissection that the point of the scalpel made an opening at the top of the ventricle, and many of the gentlemen asked how it came about. The surgeon said that he had done it by accident, and Monsieur Vallot said that he had seen when the cut was made."' Littré objects, with reason, that it is difficult to make inadvertently an incision with the point of a pair of scissors--there is no question of a scalpel--in a tough and distended membrane like the stomach during an autopsy. The illusion of the physicians present at the operation is the more easily explained because in that lesion, as it is now known, the edges of the opening are perfectly clean and sharp, very regular, so that the hole seems to have been made artificially. Jaccoud points out 'the very sharp delimitation of the ulcer, the absence of inflammation, and of peripheral suppuration.' 'The section of the tissues,' writes Monsieur Bouveret, 'is so clean that, to adopt a classical comparison, the ulcer appears as though cut out with a punch.' It varies in dimensions from the size of a lentil to that of a five-franc piece.