He dissolved eight grains in half an ounce of spirit, and rubbed first one half, and after the interval of a quarter of an hour, the second half along the spine. When this was done at the commencement of the cold fit, it very often prevented even a single recurrence. Dr. Daunt also bears testimony to this method in the fevers of South America. In _Remittent and Jungle Fever_, Quinine is a remedy of the highest value, but its exhibition requires more caution and discrimination than in simple intermittents. Dr. Maclean's treatment appears to be worthy of every attention. After premising, in most cases, a cathartic, immediately on the first signs of remission, he administers a full dose of Quinine, 10 grains, often 15, sometimes 20 grains, never exceeding that dose, and not deterred by the presence of headache or a foul tongue, nor because the remission is slight or imperfectly marked; and this dose he repeats every second hour until 30 or 35 grains have been taken before the hour of the expected exacerbation. Should the stomach be too irritable to bear it, it should be given in enema in large doses (20 grains). As soon as the second remission appears, it must be given as before until full cinchonism or distinct abatement of the disease occurs. During the remission the patient should have mild farinaceous diet, milk, chicken-broth, &c.; as soon as gastric irritability subsides, beef tea should be given, and on the first sign of exhaustion, nourishment and stimulants should be resorted to at short intervals. With regard to the administration of Quinine during exacerbations, Dr. Maclean is of opinion that in the adynamic forms of fever, as met with in some parts of India, and in neglected or mismanaged cases, where depletion has been carried too far, and the fever assumes more of a low continued type, it may be given at any period irrespective of remission. Here it requires to be conjoined with the assiduous use of support and stimulants at short intervals. As a preventive of _Malarious Fever_, the power and value of Quinine have been proved beyond a doubt. Every person engaged in forests, swamps, or low, malarious sites, should be provided with a stock of it, and four grains of it in a cup of hot coffee should be taken the first thing in the morning or in a glassful of wine later in the day. Even if it should fail, which it rarely does, no harm can result from its use, and it is essential that it should be continued for at least fourteen days after quitting a malarious locality. _Fits._ See _Convulsions_, and _Hysterical Affections_. _Flatulence, and Flatulent Colic._ Give Omum Water (318*), Lemon Grass Oil (216), infusion of Ginger (155), or of Jatamansi (184); with Mustard Poultices (251) and Turpentine Stupes (362) externally; in severe cases an enema of Asafœtida (36) will generally afford relief. See also _Bowels, Spasmodic Affections of_. _Of Children_, see _Colic_.