“Have you not had amongst your own people an instance of pestilence occasioned by the neglect of removable causes of disease?—In the summer of 1839 some remarkable cases of fever occurred in my immediate neighbourhood amongst the inhabitants in my employment, of a small cluster of houses called Littlemoor. The situation of this little spot has always been considered, and justly, as remarkably healthy and agreeable, the soil around it being dry, and not marshy, as the name would seem to imply. It is situated on gently sloping ground, about a mile from the town of Clitheroe, and freely exposed on all sides to the wind. It contained six houses and 21 inhabitants at the time of the fever. The houses are built in three distinct groups, round an irregular area of from 50 to 60 feet square. A single, inadequate, and half-choked-up drain, originally constructed more than 40 years ago, for the only cottager, then existing on the spot, was the only underground outlet for the filth, and sink, and surplus water of these habitations; the rest was carried off by a deep and open ditch filled with grass and weeds; this ditch spread out, about 100 yards to the north, into a shallow stagnant pool, in summer green and fœtid; from which was conveyed all the water that could flow during that season past and amongst the cottages at Littlemoor. Into the centre of the open area or yard was poured all the filth of the houses in open channels, and thence, by the above-mentioned underground drain, conveyed away. This state of things was bad enough, but was rendered still worse by the erection recently of a pigsty, the litter and filth of which not only obstructed the drain, but occasioned a pool of abomination of the most perilous and disgusting nature. At the time I saw it—the commencement of the fever—it was overflowing into the foundation of the principal habitation, and had infected the whole house with its stench, and was making its way by innumerable black and fœtid streams through a small shrubbery, the area of which it wholly covered, into the deep and open ditch. Believing this to be the source of the pestilence, I had the sty instantly pulled down, the filth removed, and a large drain brought up to the centre of the yard, terminating in small covered troughs to each habitation. This was in the middle of August, and from the hour of the removal of the filth no fresh case of fever occurred. The first case was on the 12th of May, and was followed by another in the same house on the 27th. In June there were three cases; and in July six; in August four; in all, 15; of which nine were the resident inhabitants, in a population of 21; and the remaining six, nurses and attendants on the sick, obtained from the immediate neighbourhood. No fever prevailed at the time in Clitheroe. One case was fatal, and the health of a most valuable