“To show the value of police regulations in removing any improper accumulations of foul, and putrid matter, where a deadly poison is generated, I have a distinct recollection that, when the cholera appeared in Macclesfield, not only was that fatal disease arrested somewhat in its progress by the active vigilance exercised by the gentlemen in seeing that in their several districts all offending deposits were removed, and all pest-houses cleansed, that for several months after the town had undergone this salutary inspection, and the people made alive to the pernicious effects of the dunghill, fever of the worst or contagious form scarcely appeared in the usual localities, although it was at the autumnal season of the year. I likewise noticed in spring-time following, when the filth had begun to accumulate on the surface in certain parts of the town, a severe return of contagious diseases, fever in all its stages, and a very fatal epidemic small-pox.” Similar cases were frequently noticed in the reports from Scotland; but when the alarm passed away, the habitual neglect of this description of cleanliness returned. In the consideration of the evidence about to be submitted as to the condition of the streets on the external condition of the residences of the labouring classes, it should be borne in mind that the external condition of the dwelling powerfully and immediately affects its internal cleanliness and general economy. The description of a large proportion of the streets inhabited by the working classes in Manchester by Dr. Baron Howard, and those of Leeds by Mr. Baker, those of Liverpool by Dr. Duncan, might be extended to Glasgow and other places. _Dr. Howard_ states:—