Corroborative experiments were made by mixing 10 to 20 per cent, of phenol with samples of the beechwood creosote, but in every case each of the tests named showed the presence of the phenol. The writer on other occasions applied single tests (the collodion test) to samples of beechwood creosote that he had an opportunity of procuring small specimens of, and satisfied himself that they were pure. The conclusion is that the wood creosote of the market of the present time is in abundant supply, is of unexceptionable quality, and reasonable in price, so that there is no excuse for the substitution of the phenol commonly sold for it. When it is directed for use for internal administration (the medicinal effect being entirely dissimilar), wood creosote only should be dispensed. The general sales of creosote by the pharmacist are in small quantities as a toothache remedy, and phenol has the power of coagulating albumen, which effectually relieves the suffering. Wood creosote does not coagulate albumen, and is, therefore, not as serviceable. This is, perhaps, the reason that it has become, in a great measure, supplanted in general sale by the coal tar creosote, to say nothing of the argument of a lower cost. * * * * * REMEDY FOR SICK HEADACHE. Surgeon Major Roehring, of Amberg, reports, in No. 32 of the _Allg. Med. Centr. Zeit_., April 22, 1882, a case of headache of long standing, which he cured by salicylate of sodium, which confirms the observations of Dr. Oehlschlager, of Dantzig, who first contended that we possessed in salicylic acid one of the most reliable remedies for neuralgia. This cannot astonish us if we remember that the action of salicylic acid is, in more than one respect, and especially in its influence on the nervous centers, analogous to quinine.