As far as I can see, Dr. Sternberg's inquiries tend to disprove the Roman experiments, and as he does not offer anything positive as a cause of ague, I can only express the hope that he will continue his investigations with zeal and earnestness, and that he will produce something positive and tangible in his labors in so interesting and important a field. I would then that all would join hands in settling the cause of this disease; and while I do not expect that all will agree with me, still, I shall respect others' opinions, and so long as I keep close to my facts I shall hope my views, based on my facts, will not be treated with disrespect. APPENDIX. Gemiasma verdans and Gemiasma rubra collected Sept. 10, 1882, on Washington Heights, near High Bridge. The illustrations show the manner in which the mature plants discharge their contents. Plate VIII. A, B, and C represent very large plants of the Gemiasma verdans. A represents a mature plant. B represents the same plant, discharging its spores and spermatia through a small opening in the cell walls. The discharge is quite rapid but not continuous, being spasmodic, as if caused by intermittent contractions in the cell walls. The discharge begins suddenly and with considerable force--a sort of explosion which projects a portion of the contents rapidly and to quite a little distance. This goes on for a few seconds, and then the cell is at rest for a few seconds, when the contractions and explosions begin again and go on as before. Under ordinary conditions it takes a plant from half an hour to an hour to deliver itself. It is about two-thirds emptied. C represents the mature plant, entirely emptied of its spore contents, there remaining inside only a few actively moving spermatia, which are slowly escaping. The spermatia differ from the spores and young plants in being smaller, and of possessing the power of moving and tumbling about rapidly, while the spores of young plants are larger and quiescent. D, E, F, and G represent mature plants belonging to the Gemiasma rubra. D represents a ripe plant, filled with spores, embryonic plants, and spermatia. E represents a ripe plant in the act of discharging its contents, it being about half emptied. F represents a ripe plant after its spore and embryonic plant contents are all discharged, leaving behind only a few actively moving spermatia, which are slowly escaping. G represents the emptied plant in a quiescent state. Figs. A, B, C represent an unusually large variety of the Gemiasma verdans. This species is usually about the size of the rubra. This large variety was found on the upper part of New York Island, near High Bridge, in a natural depression where the water stands most of the year, except in July, August, and September, when it becomes an area of drying, cracked mud two hundred feet across. As the mud dries these plants develop in great profusion, giving an appearance to the surface as if covered thickly with brick dust.