That men live at all in their obstructed and therefore poison-loaded atmosphere, is a proof of the wonderful efficiency of the protective economy of Nature within us; so wonderful, indeed, that few can believe the fact of living to be consistent with the real existence of such a deadly environment as science pretends to reveal. It is a common impression, therefore, that actual results fail to justify the alarm sounded by sanitarians. Hence the necessity for calling attention at the outset to an ample and manifest equivalent for the deadly dose of confined exhalations taken daily by all civilized men. We perceive that that dose is not lost, like the Humboldt River, in a "sink," but reappears, like the wide-sown grass, in a perennial and universal crop of diseases, almost numberless and ever increasing in number, peculiar to house-dwellers. The trail of these plagues stops nowhere else; it leads straight to the imprisoned atmosphere in our artificial inclosures, and there it ends. That marvelous protective economy of Nature within us, to which we have referred, is no perpetual guaranty against the consequences of our negligence; it is only a limited reprieve, to afford space for repentance; and unless we hasten to improve the day of grace, the suspended sentence comes down, upon us at last with force the more accumulated by delay. Now, therefore, the grand problem of sanitary science (almost untouched, almost unrecognized) proves to be no other and no less than this: What can be done to remedy the obstructive nature of an inclosure, so that its gaseous contents shall _move off_, and be replaced by pure air, as freely, as rapidly, and as incessantly, as in the open atmosphere? It happens to be the most necessary preliminary in approaching this problem, to show how _not_ to do it, for that, respectfully be it spoken, is what we have hitherto practiced, as results abundantly prove. Fallacies, both vulgar and scientific, obstruct our way. A fundamental fallacy respects the very nature of the work, which is supposed to be _to get in fresh air_. In point of fact, this care is both unnecessary and comparatively useless. Take care of the bad air, and the fresh air will take care of itself. Only make room for it, and you cannot keep it out. On the other hand, unless you first make room for it, you cannot keep it _in_; pump it in and blow it in as you may, you only blow it _through_, as the Jordan flows comparatively uncontaminated through the Dead Sea. This is a law of fluids that must be kept in view. The pure air is quite as ready to get out as to get in; while the air loaded with poisonous vapors is as sluggish as a gorged serpent, and will not budge but on compulsion. Such compulsion the grand system of wind _suction_, actuated by the sun, supplies on the scale of the universe; and this we must imitate and adapt for our more limited purposes.