We have already considered numerous _complications_ of scurvy, and shall
therefore not go over this ground again. Many of them are due to
hemorrhages or to serous effusions in various parts of the body. Another
large group in adults as well as in infants are the result of infection.
The respiratory tract is particularly susceptible, pneumonia
constituting the most common cause of death. In infants we meet with
frequent attacks of "grippe," widespread occurrence of _nasal
diphtheria_, furunculosis and torpid ulcers of the skin, pyelitis,
otitis, adenitis, etc. We have encountered nasal diphtheria--with
typical bloody mucous discharge--so frequently in connection with
scurvy, that where this local infection occurs among a group of infants
they should be carefully examined for latent or mild scurvy. Aschoff and
Koch recently have laid emphasis on the frequency with which diphtheria
complicated scurvy among adults (soldiers). Dysentery is another
complication resulting from an invasion of bacteria. Local infections
occur more often in adults than in infants--cervical adenitis following
gingival pyorrhoea, "bubo" of the groin following infection of the
lower extremity, abscess of the calf of the leg following hemorrhage
into this region.
Scurvy sometimes occurs in _epidemic form_, especially in the army, but
also, as in Russia, among the civilian population. This results when a
large group of individuals have been maintained on a limited and
inadequate ration, and especially where this nutritional condition is
complicated by intercurrent infection. It should not be interpreted as
evidence of the bacterial origin of scurvy. A few years ago the author
reported an epidemic of scurvy in connection with an outbreak of grippe
in an infant asylum. Twelve infants in one ward were affected. The signs
were atypical--an undue degree of hemorrhage occurring at atypical sites
(Table 5). It will be noted from the table that the ages of the infants,
the distribution of the hemorrhages, the development of signs (in some
instances) in spite of antiscorbutic treatment, the sharply defined
epidemic character, distinguish these cases from the scurvy commonly
seen. This is an instance where latent scurvy was prematurely changed to
acute scurvy by an intercurrent ward infection; an epidemic of grippe
precipitated a pseudo-epidemic of scurvy. It is important, especially
for army surgeons, to bear in mind that where latent scurvy exists a
bacterial invasion will lend the disorder a hemorrhagic character. This
has been noted during the recent war in connection with typhus fever on
the Eastern front, and was remarked upon during the Crimean War and our
War of the Rebellion. Some years ago Wherry made a similar observation
in the course of experiments with the plague bacillus--guinea-pigs fed
on a cereal diet developed far more hemorrhages subsequent to infection
than those which received cabbage in addition.
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