hypertrophy and degenerative changes in the vagus and all its branches."
Hess described and demonstrated by means of roentgenograms the enlarged
heart in infantile scurvy. Recently Erdheim, in an article entitled "Das
Barlowherz," reported the occurrence of enlargement of the heart,
especially of the right ventricle, in 21 out of 31 necropsies of
infantile scurvy, and concluded that a direct ratio exists between the
degree of enlargement and the intensity of the disorder. These reports
gain added interest in view of the enlargement of the right heart so
frequently encountered in beriberi, and described by Andrews in infants
dying of this condition. In addition to the definite statement of
Darling regarding adults, mention may be made of the observation of
Aschoff and Koch, that in two cases of uncomplicated scurvy there were
fatty degeneration and dilatation of the heart. Fatty degeneration of
the muscle is frequent, brown atrophy exceptional. Sato and Nambu also
found hyperæmia and atrophy with increase of connective tissue between
the muscle fibres.
The pericardial cavity contains almost invariably an increased quantity
of fluid, which may be so great as to impede the heart's action.
Adhesive pericarditis has been described. The cardiac valves are normal,
unless previously damaged.
=Lungs.=--The lungs are almost always congested, but apart from this are
remarkably free from abnormality. Smaller or larger hemorrhages are
described occasionally, which are usually considered truly scorbutic;
Andrews, however, found similar lesions in beriberi. In the necropsy of
Stephen Mackenzie's case, described by Barlow, these small hemorrhages
are stated to have resembled small red tubercles scattered throughout
the lung. There may be pulmonary infarcts. Edema of the lungs is not
uncommon, as we should expect, especially as a terminal condition.
Pneumonia, lobular or lobar, is one of the most frequent complications
and causes of death. Active tuberculosis is a not uncommon secondary
manifestation.
Subserous hemorrhages are almost the rule; if infection supervenes, the
pleuræ become thickened and covered with an exudate of pus and fibrin.
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