Secret remedies : $b What they cost and what they containBritish Medical Association
Science
Secret remedies : $b What they cost and what they contain
British Medical Association
Patent medicines
The next article analysed was a blue fluid containing a considerable
blue sediment, and smelling fairly strongly of terebene. The chief
ingredient was found to be a blue dye stuff of the oxazine or thiazine
group, much resembling methylene blue (which is the only member of
these groups ordinarily used in medicine), but differing from it in
solubility and in its behaviour with certain reagents. This constituted
the greater part of the sediment, and a portion of the dye was also in
solution. The liquid further contained a dissolved gum and a trace
of terebene; these, with a little magnesium carbonate, were all the
ingredients present. No trace of any alkaloid was found, and the
solvent was water. The gum showed no difference from ordinary acacia
gum, and was probably added to suspend the undissolved dye stuff. Water
dissolves very little terebene, and no more of the latter was present
than could be dissolved by the water; it was probably employed to give
an aromatic taste and smell, and the magnesia was doubtless used to
subdivide the terebene in the manner commonly followed by pharmacists
when dissolving essential oils in water. It thus appears that the
essential ingredient of this medicine is the blue dye stuff; it is
possible that this has been used as methylene blue, since the articles
sent out under the same name by different dye manufacturers often
differ in composition; but, as already stated, it is not identical with
the methylene blue usually met with. The total solids in the mixture,
after shaking up the sediment, amounted to 13·2 per cent., of which the
dye stuff constituted something like one-half.
A third preparation was a brown liquid of syrupy consistence found
to consist of wood tar. It was a much purer product than ordinary
Stockholm tar, and its peculiar odour indicated that it was derived,
at least in great part, from the birch; no other ingredient could
be found. This article came from Sphakia, Crete; the label bore no
directions for its use, leaving it uncertain whether it was intended
for internal or external use, but the latter appears the more probable.
The remaining articles are clearly intended for external application;
the first of these consisted of a plaster mass, in the half-pound
sticks in which such masses are usually supplied. Analysis showed the
principal ingredient to be lead oleate, with a little stearate, and
small quantities of resin and soap. These are the ingredients of the
resin and the soap plasters of the _British Pharmacopœia_, and the
proportion of soap present showed the specimen under examination to be
emplastrum resinae.
The next preparation was an ointment of Dutch origin. It contained
large quantities of ammonium alum and zinc sulphate, with a little
sodium sulphate, made up into a stiff ointment with a basis consisting
of beeswax, soft paraffin, oil, and resin. The quantities of the salts
were approximately:
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