A few years ago a good deal was heard of the wonderful cures said to be achieved by two persons who resided at Cardigan. A great deal of secrecy was observed, but it was known that a fluid was applied to the surface of the cancerous tumour. The treatment, it was stated, began with prayer, and exhortations to the patient to trust in the Almighty; the lotion or oil, which was said to be made entirely from herbs and to contain no mineral caustic, was then painted on with a brush. Unlike other empirics who profess to remove the “roots” which the knife leaves behind, these Welsh practitioners asserted that their remedy made the “roots” shrink into the original growth which then fell off like a ripe apple from a tree. The practice seemed to be to require the patient to attend daily to have the local application made for periods extending over several months. Eventually, in some cases, a mass of dried, heaped-up crusts formed, and when this became detached it was put into a bottle and given to the patient who was told that it was the cancer extracted by the treatment. In one case which was enquired into, this bottle cancer was submitted to microscopical examination; it was found to consist of crusts formed of sloughing parts of the skin and inflammatory exudation, the whole being such a mass as might be produced by the use of an escharotic. The crusts when submitted to chemical analysis were found to contain zinc chloride in considerable amount, together with a very appreciable quantity of an insoluble compound of lead. A healing oil was also supplied to help the cancer falling off, and this when chemically examined was found to contain 27 per cent. of oil of turpentine, the remainder consisting principally of an ordinary saponifiable oil, probably cotton-seed or olive oil. In addition there was a considerable amount of deposit which proved to consist almost wholly of barium sulphate, a very insoluble salt, used, under the name of permanent white, by watercolour artists. It would seem, therefore, that the statement that the applications contained no mineral caustic was inaccurate. In other patients the effect of this Cardigan treatment was more destructive. In the case of one woman who had been informed that the cancer had been cured and that she only required some tonic medicine to complete the cure, the surgeon who was called to her when she was _in extremis_ has said that he never beheld anything like it in his life; the whole breast was a necrosing mass, black and stinking, the ulcers extending up to the collar-bone and down to the margin of the ribs and across the middle line; the hand could have been inserted under the margin of the dead part all round. Some unfortunate patients persevered with the treatment although suffering pain described as excruciating.