_Dose._—One teaspoonful three times a day. The price of a bottle holding 12 fluid ounces was 2s. 9d.; the estimated cost of the contents is about 1d. OSBORNE’S MIXTURE FOR EPILEPSY. This mixture is stated to be prepared in a small town in England. The following is an extract from a circular accompanying the bottle: It scarcely ever fails to prevent the fits, loss of consciousness, convulsions, nervous twitchings, &c., of epilepsy, while at the same time it acts as a most valuable tonic; it allays irritation of the nervous system, purifies the blood, strengthens the frame, improves the general health, and helps to check the progress of disease on the intellectual faculties, and may be taken by the most delicate. The formula ascertained by analysis was: Potassium bromide 166 grains. Sugar 48 ” (= syrup Ʒj). Burnt sugar q.s. to colour. Peppermint water to 1 fluid ounce. Traces of fixed ammonia were also present. _Dose._—One large teaspoonful morning and night. The price charged for a bottle holding 5 fluid ounces was 2s. 9d.; the estimated cost of the contents is about 3d. “PROFESSOR” O. PHELPS BROWN’S VERVAIN RESTORATIVE ASSIMILANT. This preparation is recommended by the vendor— “for the positive and speedy cure of epilepsy or fits, dyspepsia, indigestion, all derangements of the stomach and bowels, and for every form of debility, no matter from what source it may arise. An unequalled tonic and nervine.” The formula ascertained by analysis was: Decoction of Vervain (2 oz. to a pint) 4 fluid drachms. Port wine 1 ” ” Rectified spirit 2 ” ” Water to 1 fluid ounce. The dose was stated to be one dessertspoonful three times a day before eating. The mixture contained 25·75 per cent. of absolute alcohol by volume, and reacted towards lead acetate and lead sub-acetate exactly like a specimen prepared according to the above formula. It also contained the same amount of extractive, and had the same specific gravity. The price is 2s. 9d. for a 6-oz. bottle. The estimated cost of the contents is about 5d. TRENCH’S REMEDY FOR EPILEPSY AND FITS. This is, or was, made by a company giving an address in Ireland. The package examined had no medicine stamp affixed. _Liquid Preparation._—The following formula refers to the liquid preparation supplied for use in the United Kingdom. The formula ascertained by analysis was: Potassium bromide 70 grains. Ammonium bromide 10 ” Sugar 72 ” (= syrup Ʒjss). Fuchsia q.s. to colour. Water to 1 fluid ounce. The dose was stated to be one teaspoonful in the morning and two at night; the price for a 3-oz. bottle is 3s.; the estimated cost of the contents was about 1d.