When the bowels are moved regularly and the motions of a natural yellow colour, the Powders had better be omitted for a time, unless great irritability be present, accompanied with restlessness, then a dose had better be given. Diarrhœa will generally be checked by giving a dose at the commencement of the attack. The directions are: When the Child is under three months of age, the Third of a Powder only is to be given; from three to six months Half a Powder may be used; when above six months a Whole Powder may be taken. The average weight of one powder was 2·4 grains; twelve powders weighed singly had weights varying from 2·25 to 2·6 grains. Analysis showed the powder to be composed of: Calomel 29 per cent. Sugar of milk 71 ” ” A trace of alkaloid was present also, and when extracted from the material of a large number of powders, was found to amount to only 0·016 per cent., or ¹/₂₅₀₀ grain in one powder. This trace of alkaloid did not show the behaviour of morphine, and did not give any reactions characteristic of any of the ordinary alkaloids, so far as it was possible to test for them on the minute amount available. The estimated cost of the materials for the powders in a 4s. 6d. box is one-third of a penny. STEEDMAN’S SOOTHING POWDERS. The powders, “with two e’s,” are stated to be prepared in the south of London, and are sold in packets, price 1s. 1½d. and 2s. 9d. per packet; the 2s. 9d. packet contained twenty-four powders. In a circular enclosed in the packet it is stated that: The good effects of these Powders during the period of Teething have now had _Fifty Years’ Experience_, during which time _Thousands of children have been relieved annually_ from all those distressing symptoms which children suffer while cutting their teeth—viz., Feverish Heats, Fits, Convulsions, Sickness of Stomach and Debility, accompanied with Relaxation of the Bowels, and pale and green motions, or Inflammation of the Gums. ... the striking superiority both in the health and strength of those children who have taken the soothing Powders during the period of Teething has induced the Proprietor to make this MUCH-VALUED MEDICINE more generally known by this advertisement. The directions are: Dose.—From one to three months, the third of a Powder; from three to six months, half of a Powder; from six months and above that age, one Powder only and no more; ... The average weight of one powder was 2·8 grains; twelve powders weighed singly had weights varying from 1·9 to 4·5 grains. Analysis showed the powder to consist of: Calomel 27 per cent. Sugar 22 ” Maize starch 50·5 ” Ash 0·5 ”