discovery was so implicit that he vaccinated his own son on three several occasions. At length he published his views in a quarto of about seventy pages, in which he gave the details of twenty-three cases of successful vaccination of individuals, to whom it was found afterwards impossible to communicate the small-pox either by contagion or inoculation. It was in 1798 that this treatise was published; though he had been working out his ideas since the year 1775, when they had begun to assume a definite form. How was the discovery received? First with indifference, then with active hostility. Jenner proceeded to London to exhibit to the profession the process of vaccination and its results; but not a single medical man could be induced to make trial of it, and after fruitlessly waiting for nearly three months, he returned to his native village. He was even caricatured and abused for his attempt to “bestialize” his species by the introduction into their systems of diseased matter from the cow’s udder. Vaccination was denounced from the pulpit as “diabolical.” It was averred that vaccinated children became “ox-faced,” that abscesses broke out to “indicate sprouting horns,” and that the countenance was gradually “transmuted into the visage of a cow, the voice into the bellowing of bulls.” Vaccination, however, was a truth, and notwithstanding the violence of the opposition, belief in it spread slowly. In one village, where a gentleman tried to introduce the practice, the first persons who permitted themselves to be vaccinated were absolutely pelted and driven into their houses if they appeared out of doors. Two ladies of title—Lady Ducie and the Countess of Berkeley—to their honour be it remembered—had the courage to vaccinate their children; and the prejudices of the day were at once broken through. The medical profession gradually came round, and there were several who even sought to rob Dr. Jenner of the merit of the discovery, when its importance came to be recognised. Jenner’s cause at last triumphed, and he was publicly honoured and rewarded. In his prosperity he was as modest as he had been in his obscurity. He was invited to settle in London, and told that he might command a practice of 10,000_l._ a year. But his answer was, “No! In the morning of my days I have sought the sequestered and lowly paths of life—the valley, and not the mountain,—and now, in the evening of my days, it is not meet for me to hold myself up as an object for fortune and for fame.” During Jenner’s own life-time the practice of vaccination became adopted all over the civilized world; and when he died, his title as a Benefactor of his kind was recognised far and wide. Cuvier has said, “If vaccine were the only discovery of the epoch, it would serve to render it illustrious for ever; yet it knocked twenty times in vain at the doors of the Academies.”