Accordingly, making Septimius take pen and ink, she proceeded to tell him a list of plants and herbs, and forest productions, and he was surprised to find that it agreed most wonderfully with the recipe contained in the old manuscript, as he had puzzled it out, and as it had been explained by the doctor. There were a few variations, it is true; but even here there was a close analogy, plants indigenous to America being substituted for cognate productions, the growth of Europe. Then there was another difference in the mode of preparation, Aunt Keziah's nostrum being a concoction, whereas the old manuscript gave a process of distillation. This similarity had a strong effect on Septimius's imagination. Here was, in one case, a drink suggested, as might be supposed, to a primitive people by something similar to that instinct by which the brute creation recognizes the medicaments suited to its needs, so that they mixed up fragrant herbs for reasons wiser than they knew, and made them into a salutary potion; and here, again, was a drink contrived by the utmost skill of a great civilized philosopher, searching the whole field of science for his purpose; and these two drinks proved, in all essential particulars, to be identically the same. "O Aunt Keziah," said he, with a longing earnestness, "are you sure that you cannot remember that one ingredient?" "No, Septimius, I cannot possibly do it," said she. "I have tried many things, skunk-cabbage, wormwood, and a thousand things; for it is truly a pity that the chief benefit of the thing should be lost for so little. But the only effect was, to spoil the good taste of the stuff, and, two or three times, to poison myself, so that I broke out all over blotches, and once lost the use of my left arm, and got a dizziness in the head, and a rheumatic twist in my knee, a hardness of hearing, and a dimness of sight, and the trembles; all of which I certainly believe to have been caused by my putting something else into this blessed drink besides the good New England rum. Stick to that, Seppy, my dear."