Significant Achievements in Space Bioscience 1958-1964United States. National Aeronautics and Space Administration
Science
Significant Achievements in Space Bioscience 1958-1964
United States. National Aeronautics and Space Administration
Biology; Space flight
Gravity has long been known as one of the major factors influencing
various life processes and the orientation of both plants and animals.
One of the most challenging problems of space research has been to
define this influence more precisely. Related to the effect of gravity
on living processes is the problem of the effects of weightlessness. Of
particular interest to psychologists are the possible modifications an
altered gravitational environment might produce in behavioral patterns
basic to the animal’s maintenance and survival, such as eating, sensory
and discriminative processes, development and maturation, and learning
capacity ([ref.91]).
One prominent method of studying gravitational effects is to simulate an
increase in gravity by centrifugation. Smith et al. ([ref.92]) and
Winget et al. ([ref.93]) have investigated the effects of long-term
acceleration on birds, primarily chickens, while Wunder (refs. [ref.94]
and [ref.95]) and his coworkers (refs. [ref.96]-[ref.99]) have used
fruit flies, mice, rats, hamsters, and turtles. The general findings are
that, when animals are subjected to a prolonged period of acceleration
of moderate intensity, they exhibit decreased growth, delayed
maturation, and an increase in the size of certain muscles and organs,
dependent on the species. With regard to the decreased growth effect,
the data of these investigators show some exceptions. When the
gravitational increase is kept below a certain limit, growth was greater
than that of controls in the fruit fly, turtle, mouse, and chicken. The
limit below which enhancement of growth was observed varied with the
species studied.
The data on food intake do not present a consistent picture. Wunder
([ref.94]) found that food intake in accelerated mice was markedly
reduced from that of nonaccelerated control animals. Smith, however,
found that in chickens, food intake increased up to 36 percent over
controls and has derived an exponential relation between food intake and
acceleration. After six generations of selective breeding, Smith has
produced a strain of chickens better adapted to prolonged exposure to
high g.
A very relevant finding of their research with birds was that exposure
to chronic acceleration in some way appears to interfere with
habituation to rotatory stimulation. Chickens who were being subjected
to chronic acceleration were given repeated rotatory stimulation tests
to estimate their labyrinthine sensitivity. This study revealed that
centrifuged animals showed a marked reduction in labyrinthine
sensitivity. This result appeared to persist after the acceleration was
terminated. In animals who developed gait or postural difficulties as a
result of acceleration, there was no evidence of a postnystagmus in
response to the rotatory stimulation test, which the investigators point
out may be evidence of a lesion in the labyrinth or its neural pathways.
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