Simpson looked no further than his own nursery and circle of close friends for the refreshment and recreation which nature demanded in the course of his busy daily life. But holidays were necessary sometimes. He exhibited all the aversion of an enthusiastically busy man to leaving his work, but would yield sometimes to the solicitations of friends and would more readily leave his patients for a time if a prospect was held out of some interesting archaeological research to be indulged in. In 1850 he suffered from an abscess, caused by blood-poisoning contracted during professional work. At the request of his friends Professor Syme was called in, somewhat to the chagrin of Simpson's old friend and colleague, Miller. It is interesting to note that in spite of the recent controversy on anaesthetics, Montgomery of Dublin, who had keenly opposed him, was amongst the first to write a sympathetic note on hearing of his illness; although dissenting from some of Simpson's professional utterances, Montgomery was influenced by the Professor's personality to respect him as a man and a worker. After this illness Simpson took a rapid run round the Continent, visiting those cities where anything professional was to be picked up. As he expressed it himself he "scampered" round the Universities, Museums, and Hospitals, seeing and hearing all that was to be seen and heard. He stowed away the newly acquired knowledge in the recesses of his mighty brain, and hastened on to the next place of interest before his companions had gained their breath sufficiently to regard with intelligent interest the objects he had already left behind. In Paris, on the occasion of one of his flying visits into a hospital, he was present at an operation, unknown to the surgeon, in which chloroform was used not only as a preventive of pain, but also for its remedial effect; after the operation the surgeon addressed his students upon the subject of chloroform, and Simpson had the pleasure of listening to a hearty eulogy of it. When, at the end, he handed in his card, the operator's delight was genuine and effusive, and the students enthusiastically appreciated the somewhat dramatic scene. On such occasions when he had to submit to the embraces of delighted foreign scientists, the exuberant manner in which they kissed him was not to his liking; even the remote strain of French blood in his own veins did not help him to enjoy the Continental mode of salutation. All over Europe his name was honoured and revered. It is said that when in later years an Edinburgh citizen was presented at the Court of Denmark the King remarked, "You come from Edinburgh? Ah! Sir Simpson was of Edinburgh!"