Femur, fracture of, 99, 127 Fertility, age limit of, in women, 26 average, estimation of, 24 old age in relation to, 23, 24, 26 social conditions influencing, 24 Fibrosis, 91, 92 Fibrositis, 155 Fibrous tissues, atrophy of, 91 Finot, J., 49 First-born, handicapping of, 38 longevity in relation to, 38 Flourens, on the duration of life, 18 Food, excess of, 56 Fractures, delay in healing of, 126, 127 tendency to, 99 France, longevity in, 40 Functional activity, danger of excess of, 54 influencing longevity, 46, 55 progressive diminution in, 115, 119, 135 Gait, disordered, 122, 147 Galileo, 53 Gallstones, 153 Gangrene, diabetic, 142 senile, 142 pipe-stem arteries with, 106 Garrod, A. E., 155 Gastric juice, composition, changes in, 115 lack of, 101 Gastro-intestinal tract, changes in, 101 Generation. _See_ Reproductive power Generative organs, internal secretion of, 70, 73–80 Genitals, external, atrophy of, 114 Giantism, 19, 20 Giddiness, 143 causes of, 151 Gilford, H., 30, 72, 88 Gisborne, Thomas, Linacre lecturer, 5 Gland activity, functional, diminution of, 115 senility in relation to, 69 Gland atrophy, 109, 110 Gland cells, life cycle of, 67 Gland secretions, influencing activity of body cells, 68, 69 Gland, endocrine, metabolism stimulated by, 81 rejuvenescence in, in relation to, 12, 73–80 Gland, endocrine, theory of old age, 70, 71, 72 Gland, endocrine, therapy during old age, 71 of prostatic enlargement, 113 rejuvenescence in relation to, 12, 73–80 _See also_ Endocrine, Pituitary, etc. Glycosuria, 126 toxic, cause of, 142 Goethe, 53 Goodpasture, E. W., 88 Gout, 154 acquired, age incidence of, 154 Gowers, W. R., 139, 144 Graves, R. J., 95 Gray, A. A., 118 Greenwood, Major, 24 Gregory IX., centenarian, 50 Growth, 60 experimental modification of, 11 influence of endocrine gland therapy on, 12, 72, 80 retardation by vitamine deficiency, 13 Habits, influencing longevity, 55 Haemoglobin, 108 Haemorrhage, 144 cerebral, 145 Hair, changes in colour of, 94 excessive growth of, 96 of the body, loss of, 96 Hale-White, W., 109, 155 Hall, Bishop, 131 Hall, Stanley, 8, 27 Haller, 91 Halsbury, Lord, nonagenarian, 51 Hands, appearance of, 93 atrophic changes in, 94 senile tremor of, 143 Harrower, 80 Haviland, John, influence on the Cambridge medical school, 6 Regius Professor of Physic, 6 Linacre lecturer, 5 Head, senile tremor of, 143 Health, definition of, 136 Hearing, impairment of, 118 Heart, atrophy of, 104 condition of, 92, 103, 104 diseases of, 149 failure, 149 age incidence of, 140 hypertrophy of, 55, 104 and blood pressure, 104 longevity in relation to, 37 senile changes in, 104, 139, 149 Heberden, W. (the elder), 4, 54