In 1865 the Five Years' War with Paraguay was commenced, a struggle in which, under the tyrant Lopez, the tiny Republic held at bay the armies of Argentina, Brazil, and Uruguay, to the utter ruin of Paraguay itself, and the virtual destruction of its male population. The struggle terminated with the death of Lopez at the Battle of Cerro Cora in 1870, after exhausting the resources of Brazilian finance. Meanwhile, in 1867, Dom Pedro opened the Amazon to the commerce of all nations, and in 1871 passed a law for the gradual abolition of slavery. Had Pedro been gifted with a child of a character resembling his own, it is reasonable to suppose that the Empire would have continued for far longer than was the case. Unfortunately, however, neither his daughter, the Princess Isabel, nor her husband, the Conde d'Eu, had succeeded in winning the sympathies of the Brazilians. Princess Isabel was markedly cold and restrained in manner, and these unfortunate traits appear to have been fully shared by her husband. The latter was somewhat deaf, which added to the apparent reserve of his manner; he was, moreover, credited with the possession of a miserly disposition. These qualities, when viewed by an impetuous and mercurial people, whose lightning sympathies demanded as rapid a response, inevitably threw their supposed possessors into disfavour. The situation was doubly to be regretted, in that both the Princess and her husband were in reality devoted to Brazil and to the best interests of the Brazilians. It may truly be said that nothing beyond the lack of demonstrative power cost them their throne. This factor in the general situation appeared at the time to be more than counterbalanced by the great popularity of the Emperor himself. The Republican spirit was growing, it is true, and the progressive State of Sao Paolo headed the movement. After a while this tendency was shorn of all disguise, and the formation of a Republic was openly advocated; but the universal desire appeared to be that the form of government should not be changed during the lifetime of the popular Emperor, Pedro II. In the meanwhile the commercial and industrial resources of Brazil were rapidly becoming extended, and the wealth of the planters increased steadily. Dom Pedro on various occasions visited Europe for the purposes of the State, and, in 1886, he started on his third journey to the Old World since the conclusion of the Paraguayan War. At no time in the history of South America has it been found prudent for the head of a State to leave his country for too long in the hands of a Regent or deputy. In this case the powers of Regent were handed over to Princess Isabel, and this lady lost little time in putting some admirable intentions into effect. This, however, she managed to effect in a manner, as is frequently the case with well-intentioned persons, which wrought no little mischief to her own interests.