Meanwhile the report of the discovery had spread. Portugal sought to take advantage of it through the theory that all heathen countries were in the gift of the Pope, which gift a Bull had already confirmed. But, Spain protesting, a subsequent Bull confirmed the Portuguese in their existing possessions, and granted them all territory that should be discovered east of a line drawn from north to south, one hundred leagues west of the Azores, while the Spaniards were to enjoy exclusive dominion over everything west of it. This was regarded as so unsatisfactory by Portugal that, at its instigation, negotiations between the two countries were opened, and resulted the following year in the conclusion of the Treaty of Tordesillas, by which it was agreed to move the line three hundred and seventy leagues west of the Azores; a most important change, because by it Portugal subsequently established its claim to the Brazils, a portion of which was found to fall east of the line of demarcation, while it could urge the further plea of having been first in the field, through the accidental deviation of Cabral. At any rate, the whole world outside Europe was leased in perpetuity to Spain and Portugal; and had the pretensions of the Holy See in things temporal as well as spiritual continued to be recognized, neither England, France nor Germany could to-day own a square yard of territory in the three greatest continents of the world. While the negotiations were in progress, preparations for a second expedition on a vastly greater scale were rapidly pushed forward. The direction of them was intrusted to a cleric named Fonseca, a capable man of business, but who for some reason or other conceived a violent dislike to Columbus, and threw every obstacle in his way. The eagerness to embark on this second voyage was far more marked than the reluctance exhibited in the first, and the best blood of Spain pressed into the service. The number of adventurers was originally limited to a thousand; but the applications were so numerous, from those who believed that fortunes were waiting to be picked up in the New World, that this was raised to twelve hundred, and fifteen hundred actually sailed in seventeen vessels from the Bay of Cadiz on the 25th of September, 1493. All was keen anticipation during the voyage, the disappointments only commenced at its termination.