Ojeda, and Amerigo Vespucci, as well as many other adventurers, followed Columbus in exploring parts of the coast of New Granada, and Amerigo gave the first regular description of the people who inhabited its shores. In the year 1508, Alonzo de Ojeda and Diego Nicuessa obtained from the Spanish crown, extensive grants in the territories now known by the names of Guatimala and New Granada; Ojeda had the country from Cape de la Vela to the Gulf of Uraba, or Gulf of Darien, included in his charter, which tract was to be styled New Andalusia; and Nicuessa was appointed to govern from the Gulf of Darien to Cape Gracias à Dios; the territory included between these points, to be named Golden Castile, and they left Hispaniola in the latter end of the year 1510, to assume the functions assigned to them. Soon after the arrival of Ojeda at Carthagena, (then called Caramari by the Indians,) he imprudently attacked the natives, and after a severe action, lost the greater part of his men, but was fortunately relieved by the arrival of the fleet of Nicuessa; he then went to the gulf of Darien, and established a colony on the eastern promontory, which place was named St. Sebastian; but being soon reduced to great extremity for want of provision, Ojeda sailed for Hispaniola, having dispatched another vessel before him to procure supplies and reinforcements for his new establishment; suffering shipwreck on the voyage, and losing all his property, he died shortly after of want. The colony being reduced to great distress, went back to Carthagena, to endeavour to fall in with the reinforcements; by great good fortune they met two vessels with their supplies, and returning to St. Sebastian, found their town destroyed by the natives; to augment their misfortunes, they run their ships ashore, but by dint of great exertion they were at last floated, when the whole colony, by the advice of Vasco Nunez de Balboa, sailed to the river of Darien, where they attacked and conquered an Indian tribe, and founded a town which was named Santa Maria el Antigua del Darien, where they received a further reinforcement by accident, in November 1510.