_Symptoms._--The symptoms are ardent thirst and profuse secretion of a pale urine of a high density (1.060 and upward), rapid loss of condition, scurfy, unthrifty skin, costiveness or irregularity of the bowels, indigestion, and the presence, in the urine, of a sweet principle--grape sugar or inosite, or both. This may be most promptly detected by touching the tip of the tongue with a drop. Sugar may be detected simply by adding a teaspoonful of liquid yeast to 4 ounces of the urine and keeping it lightly stopped at a temperature of 70 deg. to 80 deg. F. for 12 hours, when the sugar will be found to have been changed into alcohol and carbon dioxid. The loss of density will give indication of the quantity of sugar transformed; thus a density of 1.035 in a urine which was formerly 1.060 would indicate about 15 grains of sugar to the fluid ounce. Inosite, or muscle sugar, frequently present in the horse's urine, and even replacing the glucose, is not fermentable. Its presence may be indicated by its sweetness and the absence of fermentation or by Gallois's test. Evaporate the suspected urine at a gentle heat almost to dryness, then add a drop of a solution of mercuric nitrate and evaporate carefully to dryness, when a yellowish residue is left that is changed on further cautious heating to a deep rose color, which disappears on cooling and reappears on heating. In advanced diabetes, dropsies in the limbs and under the chest and belly, puffy, swollen eyelids, cataracts, catarrhal inflammation of the lungs, weak, uncertain gait, and drowsiness may be noted.