Sometimes, too, dropsical effusions in the limbs or into the cavities of the body result from the irregular and deficient circulation. Derangement of the urinary secretion, with passive congestion of the kidneys, may also appear. Endocardial inflammation is seldom fatal in its early stages, but in many cases the recovery is incomplete, for a large proportion is left with some permanent thickening of the valves, which constitutes the beginning of valvular disease. _Symptoms._--Endocarditis may be ushered in by a chill, with sudden and marked rise in temperature. The pulse rapidly decreases in strength or may become irregular, while the heart beats more or less tumultuously. In the early stages soft-blowing sounds may be heard by placing the ear over the heart on the left side, which correspond in number and rhythm to the heart's action. Excessive pain, though not so great as in acute pleuritis, is manifested when the animal is compelled to trot; very often difficulty in breathing, or shortness of breath, on the slightest exertion develops early in the attack. When the valves are involved in the inflammatory process the visible mucous membranes become either very pale or very dark colored, and fainting may occur when the head is suddenly elevated. When the valves of the right side are affected we may find a regurgitant pulsation in the jugular vein. Occasionally it happens that the heart contracts more frequently than the pulse beats--that is, there may be twice as many contractions of the heart in a minute as there are pulse waves in the arteries. The pulse is always very fast. In some cases we find marked lameness of the left shoulder, and when the animal is turned short to the left side he may groan with pain, and the heart's action become violently excited, although pressure against the chest wall will not produce pain unless roughly applied. The animal is not disposed to eat or drink much; the surface of the body and legs are cold--rarely excessively hot--and frequently the body of the animal is in a subdued tremor. In nearly all cases there is partial suppression of the urinary secretion. The symptoms may continue with very little modification for three or four days, sometimes seven days, without any marked changes. If large fibrinous clots form in the heart the change will be sudden and quickly prove fatal unless they become loosened and are carried away in the circulation; then apoplexy may result from the plugging of arteries too small to give further transmission. If the animal manifests symptoms of improvement, the changes usually are slow and steady until he feels apparently as well as ever, eats well, and moves freely in his stall or yard. When he is taken out, however, the seeming strength often proves deceptive, as he may quickly weaken if urged into a fast gait, the breathing becomes quickened with a double flank movement as in heaves, and all the former symptoms reappear in a modified degree. An examination at this stage may