Among the causes may be named: Exposure to drafts of cold air, or to cold rain or snow storms; the bites or stings of mosquitoes, flies, or other insects; snake bites, pricks with thorns, blows of whip or club; accidental bruises against the stall or ground, especially during the violent struggles of colic, enteritis, phrenitis (staggers), and when thrown for operations. It is also a result of infecting inoculations, as of erysipelas, anthrax, boil, etc., and is noted by Leblanc as especially prevalent among horses kept on low, marshy pastures. Finally, the introduction of sand, dust, chaff, beards of barley and seeds of the finest grasses, and the contact with irritant, chemical powders, liquids, and gases (ammonia from manure or factory, chlorin, strong sulphur fumes, smoke, and other products of combustion, etc.) may start the inflammation. The eyelids often undergo extreme inflammatory and dropsical swelling in urticaria (nettlerash, surfeit) and in the general inflammatory dropsy known as purpura hemorrhagica. The affection will, therefore, readily divide itself into (1) inflammations due to constitutional causes; (2) those due to direct injury, mechanical or chemical; and (3) such as are due to inoculation with infecting material. (1) Inflammations due to constitutional causes are distinguished by the absence of any local wound, and the history of a low, damp pasture, exposure, indigestion from unwholesome feed, or the presence elsewhere on the limbs or body of the general, doughy swellings of purpura hemorrhagica. The lids are swollen and thickened; it may be slightly or it may be so extremely that the eyeball can not be seen. If the lid can be everted to show its mucous membrane, that is seen to be of a deep-red color, especially along the branching lines of the blood vessels. The part is hot and painful, and a profuse flow of tears and mucus escapes on the side of the face, causing irritation and loss of the hair. If improvement follows, this discharge becomes more tenacious, and tends to cause adhesion to the edges of the upper and lower lids and to mat together the eyelashes in bundles. This gradually decreases to the natural amount, and the redness and congested appearance of the eye disappears, but swelling, thickening, and stiffness of the lids may continue for a time. There may be more or less fever according to the violence of the inflammation, but so long as there is no serious disease of the interior of the eye or of other vital organ, it is usually moderate.