Many dogs are very refractory to certain diseases, amongst these being distemper. The Commission of Veterinary Surgeons, appointed to inquire into the utility of Dr Physalix's Vaccine, has convinced the writer that it was a failure from beginning to end, and he advises all dog admirers, Masters of Hounds, etc., to steer clear of its use. There is no doubt that in course of time an anti-toxin, or some other attenuated form of distemper virus will be produced for the cure, or prevention of, this deadly canine malady. Regarding the treatment of distemper, it has been suggested that a dose of castor oil may, with advantage, be given at the outset. The author does not consider this advisable: the oil, owing to its extremely nauseating properties, tends to further weaken the animal by the production of vomition, etc. Moreover, castor oil leaves the bowels in a drier condition than before--an undesirable effect. A soft--not dysenteric--condition of the evacuations is advantageous, much of the poison being got rid by the alimentary canal in this way. A moist condition of the bowels is best maintained by the daily use of some of the natural aperient waters, such as Apenta, Hunyadi-Janos, etc., given in small doses once a day; say, every morning, taking particular care not to go too far. The superiority of these saline aperients to those of oleaginous and other resinous purgatives, is further evidenced by the fact that they also act as febrifuges, lowering the excessive heat, thus diminishing the rapid loss of flesh, so characteristic of this affection. For the husky cough give from one teaspoonful to a tablespoonful of ipecacuanha wine, just as it is. This should induce vomiting, and ought not to be repeated, at least for several days. As a rule, very satisfactory results follow its use. Inhalations of turpentine, eucalyptus, and spirit of camphor, or a little menthol, are exceedingly beneficial. Four teaspoonfuls of each of the three first-named may be mixed together, and then one teaspoonful added to half a pint of boiling water, the dog being made to inhale the steam. Five to ten drops of oil of eucalyptus, mixed with a little fine sugar, and placed inside the mouth night and morning, is good for the catarrhal symptoms of distemper, and the author can, from experience, recommend its employment. When chest complications are marked, the application of mustard paste to the sides will do good. Put the fore and hind limbs through holes cut in a thick piece of woollen blanket, and fasten it over the back. This will keep the chest warm and prevent the mustard from being rubbed off, more especially if a bit of brown paper be interposed. Stimulants are indispensable in distemper, so that bovril, claret, and brandy are required. Brand's Essence is the best for nourishment. Give it in teaspoonful doses every hour. One may add the same quantity of brandy or whisky to it.