Newly-born puppies seem predisposed to become infected with round-worms, known as _Ascaris marginata_, such infection taking place from the dam, hence the necessity for ridding her of worms, and the most suitable time to administer vermifuge medicine, in an efficacious manner, is prior to her coming in season. With reference to the preventative measures against worm infestation, speaking practically, not a great deal can be done, the sources of infection being so varied. Feeding dogs on the viscera of animals must of course be condemned, and with the abolition of this practice so will diminish one source of infection. Many so-called worm specifics are now largely advertised, rival proprietors claiming superiority and even infallibility. Some of these nostrums are given without fasting the dog, but said to be equally efficacious. This statement must be accepted with reservation, as all worm medicines act more energetically when the stomach and bowels are empty. Before administering worm medicine, it is advisable to fast adult dogs for twenty-four hours, but puppies should not be kept longer than fifteen hours without food. Although an old, but well-tried remedy against both round and flat worms, areca nut still maintains its position, and rightly so, because when given in suitable doses, and in accordance with the old rules, it seldom fails to give a satisfactory account of its action. The freshly grated nut has advantages over the powder, more especially if the latter has been kept in stock for a considerable time, as usually happens where the demand for a certain drug is limited. When combined with santonin, its action on round-worms is greatly enhanced. Areca nut, santonin, and male fern, are now all sold in capsular form, thus diminishing their nauseating effects. The average dose of areca nut for such breeds as Pointers, Setters, Retrievers, Fox and other Hounds, is a drachm and a half, combined with 8 grains of santonin, and given as a bolus mixed with honey, treacle, etc., or in a little milk, though less liable to be vomited when given without any liquid. About three hours afterwards give a full dose of castor oil. Repeat weekly, for a month if needful. A course of tonic medicine may then follow, so as to brace up the constitution. Such substances as powdered glass and other mechanical irritants ought to be avoided, being liable to set up gastro-enteritis. Powdered tin, glass, etc., belong to this class. Calomel, hellebore, pomegranate bark, spirit of turpentine, Barbadoes tar, garlic, wormwood, Kousso, Kamala, etc., have been, and still are, much used, and abused. Whatever be the drug employed, it is advisable to isolate dog both before and after dosing, so that the results can be properly noted. Through neglect of this precaution, many failures or indifferent results arise. The indiscriminate employment of worm medicines is but too frequently resorted to, and may further deplete an already exhausted system.