2. The second point I named was _the response to the Divine appeal_: 'Here am I; send me'. Cannot that be repeated in various directions among us? Thank God for the responses already made, and but for which dark and hopeless, indeed, would be human hearts and places which have been illuminated by the light of God's Salvation. But, Oh, for more ready and larger responses to the appeal which is ever sounding in our ears! Isaiah's response was a _voluntary_ one. Some people are like the horse whom his owner said had only two faults; one, that he 'took such a lot of catching', and the other that 'he would not work when he was caught'. Others have to be disciplined and broken by trouble before they fall in line with God's will. But why should not every one who names our Lord's name cry out with a ready spirit, 'Here am I, Lord; send me'? This was also _a response without conditions_; or, as we put it, an unreserved surrender, an unconditional consecration. It is a matter to rejoice over when men and women express willingness to do any service, but it is infinitely better when, coming up to the Divine altar, they say, 'Here am I, Lord; have your own way; do as you will with me; anything for Jesus--anywhere for Thee'. Have you got there yet? If not, let that be the advance which you make now, without further bargaining and reserves. But _this response came from a heart qualified to make it good_. Ah! that is the secret of all successful service. Isaiah, cleansed, sanctified, and touched with Divine Fire, was a different person from the one who lay grovelling in the dust, and crying, 'Woe is me!' Up to that moment he was too much like those around him; but now, touched, baptized, and qualified, he was fit to be God's witness and agent. That just touches the point where some of you are lacking. You need this cleansing, this 'unction of the Holy One', or you need it afresh in the face of the world's crying need. You hold back, you stumble and often fail; but why? The answer is, you need just what Isaiah got to qualify him for his mission. You must get this so as to be able to respond to God's appeal as he did. 3. Then I also spoke of the _Divine commission which followed the response_. Observe the process, 'Who will go?' 'Here am I.' '_And He said, Go_'. That is still the line upon which our Lord acts in sending out His representatives. We sometimes dwell upon the 'Come's' of the Bible, quoting the Divine invitations for the encouragement of hesitating souls. May we not with equal force quote the 'Go's' of the Book as indicating the will of God concerning our duty? You remember the Lord's 'Go' to Moses, when, appearing to him in the burning bush, God set out His plan for Israel's deliverance: 'I will send thee to bring My people out'. In the same manner the Lord gave Joshua his marching orders to 'Go over Jordan, and possess the land'. Paul had a similar experience when the Lord bade him rise and receive his commission to go to the Gentiles.