The extent to which sexual abstinence and the struggles it involves may hamper and absorb the individual throughout life is well illustrated in the following case. A lady, vigorous, robust, and generally healthy, of great intelligence and high character, has reached middle life without marrying, or ever having sexual relationships. She was an only child, and when between three and four years of age, a playmate some six years older, initiated her into the habit of playing with her sexual parts. She was, however, at this age quite devoid of sexual feelings, and the habit dropped naturally, without any bad effects, as soon as she left the neighborhood of this girl a year or so later. Her health was good and even brilliant, and she developed vigorously at puberty. At the age of sixteen, however, a mental shock caused menstruation to diminish in amount during some years, and simultaneously with this diminution persistent sexual excitement appeared spontaneously, for the first time. She regarded such feelings as abnormal and unhealthy, and exerted all her powers of self-control in resisting them. But will power had no effect in diminishing the feelings. There was constant and imperious excitement, with the sense of vibration, tension, pressure, dilatation and tickling, accompanied, it may be, by some ovarian congestion, for she felt that on the left side there was a network of sexual nerves, and retroversion of the uterus was detected some years later. Her life was strenuous with many duties, but no occupation could be pursued without this undercurrent of sexual hyperæsthesia involving perpetual self-control. This continued more or less acutely for many years, when menstruation suddenly stopped altogether, much before the usual period of the climacteric. At the same time the sexual excitement ceased, and she became calm, peaceful, and happy. Diminished menstruation was associated with sexual excitement, but abundant menstruation and its complete absence were both accompanied by the relief of excitement. This lasted for two years. Then, for the treatment of a trifling degree of anæmia, she was subjected to a long, and, in her case, injudicious course of hypodermic injections of strychnia. From that time, five years ago, up to the present, there has been constant sexual excitement, and she has always to be on guard lest she should be overtaken by a sexual spasm. Her torture is increased by the fact that her traditions make it impossible for her (except under very exceptional circumstances) to allude to the cause of her sufferings. "A woman is handicapped," she writes. "She may never speak to anyone on such a subject. She must live her tragedy alone, smiling as much as she can under the strain of her terrible burden." To add to her trouble, two years ago, she felt