11. A conference was held at the British War Office on October 14, 1918 (30), to discuss prophylactic vaccination and vaccines for treatment of influenza. Elaborate plans regarding dosage and gathering of statistics were made. NOTANDA.—For reasons already given, the reports in Series III fail to give very reliable data on which to base a knowledge of the value of preventive vaccination against epidemic influenza. _The Attempt to Prevent Pneumonia as a Complication of Influenza Through the Use of Lipovaccine_ Whitmore, Fennel and Peterson (31) developed a method of preparing an oily suspension of killed bacteria which they called “lipovaccine.” The method was used at first in making typhoid and dysentery vaccines. The advantages of lipovaccines (32) over salt suspensions are: the prevention of autolysis of the bacteria, thus increasing the length of time during which the vaccine remains active; the slow absorption of the dose, allowing the patient to continue to absorb immunity-producing substances over a period of days or weeks; the administration of a single massive dose, which does away with the three doses necessary when salt suspensions are used; and perhaps, also, the direct reduction in the toxicity of the dose by the lipoid material. Based upon the classification of pneumococci by Dochez and Gillespie (33) in this country, and by Lister (34), (35), (36) in South Africa, and upon the latter’s successful use of anti-pneumonia vaccine on the Rand, an anti-pneumonia lipovaccine was prepared at the Army Medical School which contained approximately 10,000,000,000 each of types I, II and III pneumococci. The vaccine was made by growing the pneumococci in dextrose broth, centrifuging them out of the broth with a sharpless milk centrifuge, drying the sediment at 55° C., weighing it out so that each cubic centimeter of the finished vaccine contains 0.83 m.g. of each type, and making a suspension of them in olive oil. More recently cotton-seed oil has been used.