Studies on Epidemic Influenza: Comprising Clinical and Laboratory InvestigationsUniversity of Pittsburgh. School of Medicine
History
Studies on Epidemic Influenza: Comprising Clinical and Laboratory Investigations
University of Pittsburgh. School of Medicine
Influenza; Influenza Epidemic, 1918-1919
And lastly, the frequency with which an
inflammatory œdema occupied the lungs in the cases of influenza was in
quite striking contrast with the dry fibrinous lesion of common
pneumonia. This wet state of the lung was but a stage in the
inflammatory process varying in its extent in the different periods, but
nevertheless inducing a character in the early pulmonary lesions which
was quite foreign to our usual finding. This wet state also assisted in
modifying the subsequent picture so that when the lung assumed its gray
appearance it was rather of a slimy character than of the firm dry
nature. In this late gray stage the slimy lung somewhat resembled the
appearance of unresolved pneumonia where this condition had been brought
about by a new infection upon the original cause of the pneumonia.
It is incorrect in influenza pneumonia to speak of the lesions as lobar
pneumonia or broncho-pneumonia if by these terms we have in mind the
pathological characters observed in the pneumococcic pneumonia with its
lobar or bronchial distribution. Influenza-pneumonia appeared with both
lobar and lobular characteristics. Nearly every case had both types of
lesions present, but the nature of the inflammatory process is so
decidedly different from that of the ordinary endemic pneumonia that a
confusion in the interpretation is likely to arise and in fact has
already raised a considerable polemic. Influenza-pneumonia is commonly
lobar, lobular or bronchial in distribution. It is, however, not of the
characters that are associated with the lesions designated under these
terms. When, therefore, we here use the word “lobar” we mean lobar _in
distribution_ but not lobar in type. As will be seen from our table, it
was usual to have multiple lobes involved. But the lesions, not only in
the different lobes varied in their character and distribution, but even
within the same lobe a variety of types was present.
TABLE VII
═══════════════════════════════════════════════╤═══════════════════════
Day of Pneumonia on Which Death Occurred │ No. of Cases
───────────────────────────────────────────────┼───────────────────────
Second │ 2
Third │ 4
Fourth │ 7
Fifth │ 6
Sixth │ 7
Seventh │ 3
Eighth │ 1
Tenth │ 1
Twentieth │ 1
───────────────────────────────────────────────┴───────────────────────
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