In two cases we observed very interesting lesions in the _bladder_. These two individuals during life had been excreting markedly blood-stained urine for some days preceding death. In the one case the hemorrhage was so marked that on standing, about one-tenth of the urine was composed of sedimented red blood cells. It was assumed that the hemorrhage was of kidney origin until the autopsy revealed a simple cloudy swelling of the kidney associated with a hemorrhagic state of the submucosa of the bladder. In both cases the posterior wall of the bladder was heavily infiltrated with blood so that the mucosa was raised from the surface and the prominent folds showed a superficial erosion with small points of greenish necrosis. This bladder hemorrhage was concomitant with hemorrhagic foci elsewhere in the body, pericardium, pleura, stomach and intestine. Alone in the bladder however, the hemorrhage formed a distinct mass and allowed a considerable escape from the lesions on the surface. These areas of hemorrhage were not infected and showed no local inflammatory reaction. They also appeared to be toxic in origin and resembled the hemorrhages occurring in the muscles of the abdomen. Changes in the _adrenal_ gland were noted in 14 instances. In all of these there was the picture of what is commonly known as cloudy swelling of the cortex and, in addition to this, in three cases small petechial hemorrhages were observed. The so-called cloudy swelling of the adrenal consists largely in a loss of the bright golden appearance of the cortical tissues accompanied by soft œdematous swelling. The tissues change color to a brown or clay color, and it is not uncommon to observe that the inner zone of pigmentation is more diffuse. There is no sharp demarcation between the layers of the cortex. With this alteration in the outer structure of the adrenal, the medulla not uncommonly appears smaller. This change is more apparent than real, and we have not been able to observe any definite lesion in the nervous portion. At times we believed that the inner tissue appeared more cellular, but it was not possible to determine any specific alteration in the cells.