Studies on Epidemic Influenza: Comprising Clinical and Laboratory InvestigationsUniversity of Pittsburgh. School of Medicine
History
Studies on Epidemic Influenza: Comprising Clinical and Laboratory Investigations
University of Pittsburgh. School of Medicine
Influenza; Influenza Epidemic, 1918-1919
The glycosuria and glycæmia were transient, and we feel that they do not
represent diabetes mellitus. Most of the patients of this class had long
since recovered from an attack of influenza, and came to the hospital
usually for treatment of various nervous conditions, which at times
simulated neuritis, or otherwise one saw manifestations of general
nervousness, not unlike hyperthyroidism. In all probability, we were
dealing with a hyperglycæmia associated with a hyperactive thyroid
gland. So, after all, the glycosuria, even though rare, is not
bewildering. Symptoms and signs of toxic goitre in direct relation to
the epidemic we claim to have seen, and one is justified, temporarily at
least, in having the thyroid gland father our transient glycosuria.
In relation to the positive sugar findings, we have had numerous
negative examples of almost equal interest. Furunculosis is a very
common sequel of the epidemic. It is well known that in furunculosis
there is a hyperglycæmia, but no glycosuria and no acetone or diacetic
acid in the urine. All our blood sugar readings were above the normal,
and at times unusually high. They varied from .2 to .41. This last
unusually high amount was in a young physician with recurrent
furunculosis following influenza. There was no glycosuria at any time.
Elimination of carbohydrates not only brought the blood sugar to normal
limits in the course of a week, but also assisted in the cure of the
furunculosis, but in a longer time. In all of this group we saw no
incidence of polyuria or glycosuria.
_Hematology_
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