Human experimentation in medicine -- Fiction; Suspense fiction
"Well," he began, "to go back to the very beginning of my interest in
stem cells the focus of our research has been directed toward
challenging the notorious Hayflick limit. Back in the 1960s, Professor
Leonard Hayflick discovered that when tissue cells are taken from the
body and cultured in a laboratory dish, those cells grow and divide
about fifty times, give or take, and then they stop. They have reached
old age, senescence. The physical basis of the Hayflick limit is a
section of DNA known as telomere, which gets shorter each time the cell
divides. Eventually the telomeres become so short that all cell
division stops. It's like an internal clock telling them the game is
over. They've had their innings."
"And you're saying you've found a way to beat the clock, to stop the
telomeres from getting shorter?"
"All cells possess a gene known as the telomerase gene, which can
restore the telomeres to their youthful length. But in most cells the
gene is permanently repressed and inactive. It is only found in egg and
sperm cells, and in cancer cells." He gazed away for a moment as though
collecting his thoughts. Then he turned back. "However, we've found
that by isolating and inserting an active copy of the telomerase enzyme
into adult stem cells, which can be found in minute quantities
throughout the body, we can set their clock back to zero. We extract
cells, 'immortalize' them with telomerase, and then return them to the
body as a youthful infusion."
"And is that what you'd be doing for Mom?"
"There'd be a series of injections, but given what appears to be her
level of mental awareness right now, the procedure probably can be
accelerated." He patted Nina on the shoulder.
"All right," Ally said "but can you use the same procedure for
someone's heart?"
"Well, yes and no," he said. "Did you bring your medical records? I
should have a look at them before making any pronouncements."
To prepare for this moment, she'd printed off a copy of the medical
files she'd scanned into her computer.
"There're a lot of files," she said, opening her bag. "I've got copies
of my EKGs over the past eleven years. Dr. Ekelman, my cardiologist,
says my condition is getting progressively worse."
She took the folder out of her bag and handed it to him. He flipped
through the files with what seemed an absent manner, almost as though
he already knew what was in them and was just going through the
motions. Then he looked up.
Public-domain text, read in full here on John Shaqi.
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