Fever due to vertebral subluxation alone without any secondary cause operating is very rare. Ordinarily fevers come about in this way. A subluxation occurs which weakens tissue and permits germ invasion; toxins enter the circulation from the germ action and motor reaction increases the original subluxation and causes local inflammation; germ activity is favored by the increasing degree of abnormality and toxins from rapid tissue destruction are added to those already present. The poison-loaded blood then affects the general centers for heat regulation, blood becomes internally engorged, and a chill (internal fever) followed by general increase of temperature occurs. At this juncture any subluxation previously existing is likely to be increased and to add its quota of harm to the rapidly developing picture. Our problem is to find the original subluxation which controls the site of the original pathologic change and to correct that. In nearly all cases where this is done, even partially, the body is enabled to care for the remainder of the damage and to throw off the accumulated toxins. It is not uncommon that the temperature falls two degrees in five or ten minutes after a proper adjustment. We expect always to abort or check a fever in twenty-four hours or less. There are cases in which the temperature drops after adjustment but presently rises again. This indicates the virulence of the autointoxication or that some other area of poison production is operating than the one our first adjustment would control. A correct diagnosis will enable one to give specific adjustment and check practically any fever except a chronic one with much tissue destruction already accomplished; even some of these yield. The commonest cause of fever is at the fifth or sixth Dorsal vertebra, long known as Center Place, or Fever Center. Here emerge many pre-ganglionic fibres which distribute their impulses through lower neurons in the sympathetic system to the coeliac plexus and thence to the blood-vessels supplying the major portion of the abdominal viscera. Adjustment here causes a sudden contraction of these abdominal vessels and a forcing of the blood to the surface with rapid cooling. Often, however, this adjustment is followed by a recrudescence which indicates that some other vertebra must be adjusted. Many fevers, such as typhoid, pneumonia, tonsilitis, etc., yield to specific local adjustment without any involvement of the so-called Center Place.