In the following tables it has been found best to insert in parentheses the capital letter (P) to call attention to any statement in support of which we have gathered less than all three forms of admissible evidence and which is therefore as yet presumptive. It is well, however, for the practitioner to be careful lest he regard too lightly such presumptive statements. Unless there is very strong and reasonable ground for such presumption or a general belief in its correctness all mention of it is omitted. Those labelled presumptive are merely so indicated because they have not yet been proven and not because they have failed to serve as a convenient and useful guide to adjustment. For each presumption offered there is either clinical or anatomical justification but not both. SPECIAL NERVE CONNECTIONS This section does not purport to state with any degree of completeness the various nerve-paths by which spinal vertebrae come into relation with all, or nearly all, the peripheral organs of the body. It merely points out some of the more interesting and important connections, some of the paths which serve to explain the common effects of vertebral adjustment. It is not expected that this resume of the subject will be more than suggestive to the student; certainly it cannot, in so brief a space, be a complete exposition. Outline of Nerve System Let us begin with the observation that almost every organ of the body, including the central nerve organs themselves, may be adversely affected by spinal subluxation impinging spinal nerve axons at their exit from, or entrance through, intervertebral foramina, or by spinal subluxation producing direct impingement upon some part of the sympathetic system and similarly interfering with its power to functionate. The Nerve System may be divided into two great divisions, the central axis and the peripheral system which distributes nerve energy from, and brings stimuli to, the central axis. The central axis consists of the brain and spinal cord; the peripheral system of 12 pairs of nerves attached to the brain and having exit (except the eighth) through foramina in the base of the cranium, 31 pairs of spinal nerves emerging through intervertebral foramina whose parts are movable upon each other (except the foramina for sacral and coccygeal nerves), and an intricate system of sympathetic fibres and ganglia arranged in a double chain of ganglia in front and at the sides of the vertebral column, three great prevertebral plexuses, the cardiac, coeliac, and hypogastric, and numerous scattered ganglia and communicating cords which bind the ganglia together and connect them with spinal or cranial nerves and with the periphery.