_Symptoms._ In the horse which fails under severe exertion there are the dilated nostrils, the labored breathing, the deep, almost convulsive action of the flanks, the hanging on the reins, the slacking of the pace, the unsteadiness of gait, and lastly the fall. There may now be noticed the protruded bloodshot eyes, the agonized expression of countenance, the extended head, the pallor, and later the blueness of the nasal mucous membrane, the short, panting breathing, accompanied by a roaring noise alike in inspiration and expiration, and the small, weak, rapid pulse often imperceptible at the jaw. If the animal has been stopped short of having fallen, or if he is able to get upon his feet, he stands with his limbs apart to secure his stability, and with the elbows turned out to facilitate the expansion of the chest. As the breathing becomes panting the respirations are less deep, the ribs are maintained permanently drawn outward, and the flanks rise and fall to a limited extent only but with great rapidity (eighty to one hundred per minute). Auscultation may detect at first an increase in the pitch of the respiratory murmur, and the presence of the finest possible _crepitation sound_. Soon the murmur decreases uniformly. The extremities are cold, and in this coldness the general surface to some extent participates even though it may be covered by perspiration. Tremors or rigors are present. The heart is felt behind the left elbow to beat tumultuously. If blood is drawn it flows in a thin, black, tary stream. In some cases blood more or less frothy is discharged from the nostrils as the result of rupture of pulmonary vessels. In the fulminant cases in =cattle= respiration is rapid, even panting, wheezing, the expiration attended by a hoarse grunt, sometimes nasal hemorrhage, great prostration, profuse perspiration, a stupor sets in and the animal falls and dies, with more or less struggling.