Text book of veterinary medicine, Volume 1 (of 5)Law, James
Science
Text book of veterinary medicine, Volume 1 (of 5)
Law, James
Veterinary medicine
a. BACILLUS OF FRIEDLÄNDER. This is a short rod with rounded ends, often
merely oval, occurring in pairs, or chains of four, and under given
circumstances surrounded by a transparent gelatinous capsule. It is
ærobic, nonmotile, does not liquefy gelatine, nor sporulate, and in
gelatine stick cultures has a nail-like growth. This was found by
Friedländer, Frobenius, Weichselbaum and Wolf in the pulmonary alveoli
in a small proportion of cases of croupous pneumonia in man. The
cultures, injected into the lungs of animals, killed one dog (out of
five), six Guinea pigs (out of eleven), and thirty-two mice (all the
injected). Lesions were intense congestion of the lungs, seropurulent
pleural effusion, and enlarged spleen, while the bacillus swarmed in the
blood and exudate.
MICROCOCCUS PNEUMONIÆ CROUPOSÆ. First found by Sternberg in his own
saliva in health, and by Pasteur in the saliva of a rabid child.
Afterward found in the great majority of lungs affected with croupous
pneumonia in man, by Talamon, Salvioli, Sternberg, Fränkel,
Weichselbaum, Netter, Gamalei, etc. Later it was found in meningitis, in
ulcerative endocarditis, in arthritis, in otitis media, and in acute
abscess in man.
It is a _spherical_ or _oval coccus_, arranged in pairs, in fours, or
exceptionally in eights or tens. Lanceolate forms are the rule in the
blood of animals, and circular in artificial cultures. It stains readily
in aniline colors and by Gram’s method, grows in ordinary culture media,
at 37° C. in the absence of free acid, and in gelatine stick cultures as
small, white colonies along the line of culture, without liquefying the
gelatine. It dies in ten minutes at 52° C. (Sternberg). Its virulence
lessens in artificial cultures, but is restored by passing through the
body of a susceptible animal.
Injection into the lungs or trachea of rabbits, mice, sheep and, less
certainly, Guinea pigs, produced distinct fibrinous pneumonia filled
with the microbe. In dogs, subcutaneously, it caused abscess, but in the
lungs an acute fibrinous pneumonia which only exceptionally proved
fatal, recovery usually taking place in ten to fifteen days.
Klemperer induced immunity, sometimes lasting six months, by intravenous
injection of filtered cultures.
DIPLOCOCCUS PNEUMONIÆ EQUINA. First found by Schütz in the lungs of
pneumonic horses in 1887. It is an oval coccus arranged usually in pairs
or in threes or fours, and surrounded by a transparent envelope. It
stains in aniline colors but not by Gram’s method. It is ærobic and
grows in gelatine at ordinary temperature without liquefying it, and in
stick cultures forms a line of small, white, separate colonies which do
not coalesce by growth. Does not grow on the surface of the gelatine
around the puncture. Line cultures on agar are in colonies like minute
transparent droplets. In bouillon it develops long chains.
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