_Lesions._ From the coccidium tenellum these are mainly found in the cæca and consist in intense inflammation, white lines formed by the parasitic colonies, desquamations of the epithelium and erosions and ulcers. In the early stages and in the absence of diarrhœa there may be simply thickening and induration of the mucous membrane and whitish colonies of the parasites. When there has been diarrhœa the contents are serous, or seropurulent, brick red, and filled with epithelial cells, red globules, leucocytes, fat globules and coccidia. The gregarinæ are not confined to the cæca but scattered over the whole intestinal canal as white spots in the submucosa surrounded by congestion and degenerative changes. It has been found complicated with false membranes. _Symptoms._ Dullness, anorexia, ruffled feathers, sunken head, trailing wings, slow uncertain gait, plaintive cries, with diarrhœa, passing through serous, brick red, and bloody. In small chicks it may be whitish and followed by constipation. Death is usually an early result. _Treatment._ Hyposulphite of soda with carminatives (fennel anise, coriander, ginger, and gentian) has been given in boiled milk or bread. Quinia and iodine might be tried. _Prevention._ Avoidance of infected roosts and runs, and above all of infected streams, wells and ponds, and the removal and cremation of the sick, followed by thorough disinfection, are much more promising than therapeutic treatment. GASTRO-ENTERITIS FROM CAUSTIC ALKALIES AND ALKALINE SALTS. Ammonia: Counter-irritation, fauces, larynx, bronchia, congestion and softening of the gastric mucosa, loose blood clots, solution of globules, dysphagia, salivation, in carnivora and omnivora vomiting, diarrhœa, white fumes with muriatic acid.—Ammonia carbonate: less corrosive, same symptoms.—Potash lye, deep corrosion, gastric congestions, fluid, blackish red blood.—Soda lye.—Carbonates of potash and soda, less violent, tests for potash and soda. Treatment: weak acids, demulcents, anodynes. =Aqua Ammonia.= Lethal dose pure, horse 1 oz. and upward; cattle 2 ozs.; dog ½ dr. There may be sudden death from abstraction of water and cauterization of the fauces and larynx including at times the bronchial mucosa. In other cases death occurs later from gastro-enteritis, the mucosa of the alimentary canal being congested, softened and covered with bloody mucus. The blood in the vessels is of a dark red, coagulates imperfectly and the blood globules are dissolved changing the color to black, and then brownish red. Prior to death there is great distress, salivation, inability to swallow, swollen tongue, frequent pulse and respiration, cough, spasms, and sometimes the odor of ammonia. Retching and vomiting may be a feature in carnivora and omnivora, and diarrhœa if the case is not promptly fatal. The urine is not rendered alkaline. White fumes with muriatic acid indicate ammonia.