Botulism. Racial immunity. Acquired immunity. Gastric secretions, protective. Bacteria in septic beef, old brine, stale fish, privy air. Symptoms: sudden onset, colic, nausea, retching, vomiting, septic vomit, fever, tender abdomen, bloody, fœtid, mucous diarrhœa, prostration, death in three to twenty-four hours. Lesions: of gastro-enteritis, ingesta fœtid, congestions and petechiæ of other organs. Treatment: emetic, laxative, diuretics, potassium iodide, antiseptics, demulcents, stimulants. _Causes._ What is called _botulism_ in man is not uncommon in carnivora. Eating carcasses of animals that have died of disease, of poisoning, etc., in a raw condition and too often in an advanced state of putrefaction, they are liable not only to infection by the pathogenic or poisonous microbes, but also to direct poisoning by the ptomaines and toxins. There are however certain protective conditions. Accustomed as this class of animals is to the consumption of such food, they have by selective evolution acquired an insusceptibility to many such poisons which would prove deadly to the herbivora. Again the mature dog or cat has already been subjected to many of these poisons and having survived them has acquired an immunity which renders it comparatively safe for the future. The antiseptic power of the gastric secretion of the dog may be easily shown, by letting him bolt a moderate piece of putrid meat, and killing him ten or fifteen minutes later when the mass will be found in the stomach without odor of decomposition. He succumbs to the poison either when the quantity ingested is too large, or when the digestion is from any cause deranged and the gastric secretion impaired. Anthrax flesh may produce pharyngeal or intestinal anthrax in the dog. In the animal with temporarily impaired immunity the more virulent septicæmias may prove infecting. From putrid beef the following pathogenic bacteria have been isolated: 1. Gärtner and Basenau have independently isolated =bacillus bovis morbificans= which forms clear colonies on the surface of peptonized gelatine, and brownish ones beneath the surface, and coagulates milk in 24 hours. This is short with rounded ends, very motile, non-liquefying, and capable of surviving the freezing temperature. Its toxins are not destroyed by boiling. It causes enteritis, or, subcutem, debility, somnolence, and stupor. This bacillus was pathogenic to mice, rats, guinea-pigs, rabbits, goats and calves but had little effect on dogs or cats. 2. The =bacillus of Poels= which produces paralysis. 3. The =bacillus of Gatky= which performs very rapid gyratory movements only, and is not found in the muscles. =Old Brine= is as poisonous for the dog as for pigs. Six to nine ounces proved fatal, (Reynal). =Stale Fish= has been known to prove poisonous in the same way. Three dogs that were made to breathe the air over a foul privy were seized with vomiting, fever and diarrhœa.