Horse especially suffers. Enzootic in given Alpine Valleys, along Rhone, in Mississippi Valley and bottom lands. Acclimatizing fever. Old, lymphatic, large heads, narrow foreheads predisposed. Geldings. Causes, heredity, cerebral and meningeal congestion, cranial traumas, venous obstruction, tumors, false membranes, fodder or water poisoning, overwork, insolation, prolonged moist heat, hepatic, gastric, and pulmonary disorders. Symptoms: form of head, stupid expression, irresponsive ears, pendent lips, sluggish movements, crossed legs, slow mastication, dips face in water, intractable by halter or rein, unable to back with rider, or wagon, drags back fore limbs, worst in hot damp weather, in sunshine, or after work, or with full stomach. Paroxysms of excitement. Lesions: excess of arachnoid, subarachnoid or ventricular fluid, atrophy of ganglia and convolutions, ependyma thick, opaque, sclerosis, brain anæmic. Tumors, nature. Experimental cases. Prognosis, incurable, better in cool season. In cattle, sheep, swine and dogs. Treatment: derivatives, nerve stimulants (nux), puncture, pilocarpin, purgatives, Jurisprudence. Notify seller in 9 days (France), 15 (Bavaria), 21 (Wurtenberg, Baden), 28 (Hesse, Prussia), 30 (Austria). Examination by expert. Dropsy of the ventricles is common in the horse in certain countries and districts, yet even there it is uncommon in cattle, sheep, swine and dogs, save as a congenital affection. It is reported as enzootic in some Alpine valleys and along the Rhone, attacking especially the mares and immature horses so that breeding becomes impossible. Mauener who reports this says that in the same localities encephalic diseases are more common in man. In America it appears to be most frequent in the rich bottom lands of the Mississippi valley and of the Southern States. Northern horses taken to the Gulf States though they may not suffer to this extent, are liable in the first year to show weakness, debility, and lack of vigor which is spoken of as the =acclimatizing fever=. Elsewhere the affection is one of the old horse in which the vital powers begin to fail. Common breeds of horses with lymphatic temperament, large head and narrow forehead have been found to be especially predisposed. Geldings are said to be most liable on account of the arrested development of the brain, but with the great preponderance of geldings among work horses, it is dangerous to generalize too far.