As medicinal treatment Large advises to give at the outset 1 oz. aloes with one or two drs. of solid extract of belladonna and as an eliminant, derivative and nervous sedative there is much to be said for it. In case the difficulty of swallowing should prove a serious barrier a hypodermic injection of ½ dr. barium chloride, 1½ to 2 grs. eserine, or 2 grs. hydrochlorate of pilocarpin together with ¼ grain of atropin, may be employed. As a substitute for atropin, ergot, potassium bromide, chloral hydrate, chloroform, or phenacetin have been tried in different cases with varying results. Iodide of potassium has been employed with advantage in the advanced stages and in convalescence, and may be usefully employed in the early stages as a sedative to the nervous system, a deobstruant and an eliminant, if not as a direct antidote, to the toxins. Bleeding is generally condemned, yet in acute cases where there are indications of active brain congestion, threatening convulsions or coma it may tend to ward off a fatal result. Cold applications to the head are generally commended. Bags of ice or snow, irrigation with cold water, or cooling by running water at a low temperature, through a pipe coiled round the head or extended along the spine, will meet the purpose. Applied continuously this constringes the blood-vessels within the cranium as well as on its surface, lessens the exudation, and controls the pain and spasms. This may be advantageously associated with warm fomentations to the feet and limbs, friction, or even the application of stimulating embrocations to draw the blood to these parts. In the smaller animals even warm baths may be resorted to as a derivative, cold being meanwhile applied to the head and spine. This not only lessens the vascular pressure within the cranium, but secures elimination of toxic matters by both skin and kidneys. Cold pure water should be constantly within reach. A most important thing in the horse is to put him in slings, if he is at all able to stand with their assistance. In decubitus he rests on his side, with the head on the ground, and lower than the splanchnic cavities. The result is a gravitation of blood toward the head. In the sling, with the head fairly raised the gravitation is the other way and the head is depleted. If the patient is too ill to be maintained in the sling, he may be packed up with bundles of straw on each side, so that his breast may lie on a thickly littered bed, and his head may be elevated. When convalescence sets in care must be taken to nourish with non-stimulating, easily digested food, gruels, soft mashes, pulped or finely sliced roots. In vomiting animals rectal alimentation may become necessary. The rise of cranial temperature or the aggravation of brain symptoms should be met as needed by the local application of cold, and potassium iodide and iron or bitter tonics may be given if they do not interfere with digestion. ABSCESS OF THE BRAIN.