Text book of veterinary medicine, Volume 3 (of 5)Law, James
Science
Text book of veterinary medicine, Volume 3 (of 5)
Law, James
Veterinary medicine
=Oxalic Acid= (C_{2} H_{2} O_{4}) appears to be secreted in small amount
by healthy kidneys and it may also come from the splitting up of uric
acid after secretion. It is augmented by feeding agents rich in oxalic
acid (beets, fresh beans, asparagus, tomatoes). Pathologically it
abounds in certain indigestions, and is associated with lameness and
emaciation. Test: Add lime water to the urine, and the white oxalate of
lime is precipitated.
=Allantoin= (C_{4}H_{6}N_{4}O_{3}) is found in the urine of sucklings
(calves) during the first few weeks of life, in pregnancy and when on a
meat diet. It diminishes with the increase of vegetable food.
=Xanthin= (C_{5}H_{4}N_{4}O_{2}) is found in urine as a result of
imperfect oxidation of nitrogenous matters especially, which would
otherwise pass into uric or hippuric acid. Its immediate antecedents in
such transformation are guanin and hypoxanthin or sarkin. It is a rare
constituent of urinary calculus.
=Hypoxanthin= (C_{5}H_{4}N_{4}O) is produced from fibrine in gastric and
pancreatic digestion and in putrefaction, and is especially abundant in
leucæmic subjects.
=Cyanuric Acid= (C_{20}H_{14}N_{2}O_{6}) occurs in dog’s urine.
=Leucin= (C_{6}H_{13}NO_{2}) and =Tyrosin= (C_{9}H_{11}NO_{3}) are
products of pancreatic digestion of proteids, and the former occurs
normally in the spleen, thymus, thyroid, liver, salivary glands, and
urine. Both are present in large amount, in the urine, in acute atrophy
of the liver. Test for leucin: Evaporate carefully to dryness with
nitric acid: the residue, if leucin, will be almost transparent and turn
yellow or brown on the addition of caustic soda. If now heated with the
soda it forms an oily drop. Test for tyrosin: treated with strong
sulphuric acid, gently warmed and chloride of iron added, it gives a
violet color.
=Albumen= is an important morbid constituent of urine, which appears in
a great variety of diseases (nephritis, pneumonia, epilepsy, anæmia,
leucæmia, diabetes, hæmaturia, hæmoglobinuria, hydræmia, infectious lung
diseases, cardiac obstruction, venous stasis in the kidney, dermatitis,
burns, lesions of the crura cerebri, floor of the fourth ventricle,
spinal cord, or renal vaso-motor nerves). It also occurs after violent
exertion, in poisoning by strong acid, phosphorus, arsenic, lead,
mercury, opium or alcohol, and when an excess of albumen is injected
into the blood. All forms of albumen may enter the urine, but the most
common are serum albumen, globulin of serum, propeptone and peptone. A
simple test is to acidulate the urine with acetic acid and boil: if the
precipitate does not dissolve on addition of nitric acid, it is albumen.
Sulphosalicylic acid added to the urine will cause a precipitate in
urine containing only ¹⁄₅₀₀₀₀ of albumen.
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