This has been noticed most commonly in the mare, which from a quiet docile animal, has become very ticklish, especially in the region of the flank, kicking on the slightest touch, or even when approached and showing an amount of nervous apprehension, that may render her useless, for work. The ovaries are usually found to be enlarged, diseased and very sensitive. Œstrum may be in some cases constant and excessive and in others entirely suspended. Such cases are difficult or dangerous to shoe. In one case recorded by Thierry, handling of the flank promptly induced an epileptic attack. Cows with nymphomania (bullers) are often victims of this condition. The only remedy is castration, which is best performed by the vagina. The shorter the period of the irritability the more perfect is the cure. In some old standing cases the vicious habit may have become so fixed, that it is continued in spite of the operation. HÆMORRHAGE ON THE OVARY. Mare and Cow: genital excitement, mechanical injury, diseased ovary in unimpregnated, ovulation with bleeding, falls, slings. Lesions: old degenerations, productive inflammation, varicosities, aneurisms, torpid vessels, blood staining, clots, follicular or not, ruptures into peritoneum, amount, microbes usually absent. Symptoms: obscure, arched, stiff loins, colics, recumbency, large tender ovary. Shivering, fever, anorexia, anæmia, surface coldness, unsteadiness, blood from vulva, liquid in abdomen fluctuates. Treatment: cold, ice, snow, on loins, cold acid drinks, tannin, iron chloride, matico, gelatine, subcutem atropin, ergotin, viburnum, derivatives, castration. This has been seen in the mare and cow especially in connection with genetic excitement and mechanical injuries, and more especially pre-existing disease of the ovary. Trasbot notes that it has always been in the absence of pregnancy, a fact which we can easily explain on the ground that most active diseases of the ovary render the animal barren. Gestation like castration, calms the genetic instincts, and prevents the recurrence of œstrum with its vascular excitement, general and ovarian, which characterizes the unimpregnated condition. The normal rupture of the Graafian follicle and escape of the ovum is attended by some effusion of blood which passes through a series of changes preparatory to absorption. A more extensive bleeding, at the time of œstrum or otherwise, into a follicle or intrafollicular, and with or without rupture of the albugenic tunic constitutes the morbid hæmorrhage. Among mechanical causes may be named violent exertion, falls, and suspension in slings.